The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes

A major portion of all of acute child neurology involves the neurological complications of infectious diseases. However, none of the currently available excellent texts on inf- tious disease focus specifically on the neurological aspects. Drs. Neil R. Friedman and Leslie L. Barton have filled this important void with a superb, multi-authored text, addressing directly "the neurological manifestations of pediatric infectious diseases and immunodeficiency syndromes. " The book is organized logically according to the responsible microorganisms and addresses sequentially a broad spectrum of viruses, bacteria, fungi, rickettsiae, spirochetes, mycobacteriae, and parasites, as well as cat-scratch disease and human immunodeficiency virus (HIV) infection. The chapters are consistently similar in organization and begin with an introduction that provides a synopsis and perspective. The substance of the chapters follows in sections devoted to epidemiology, pathog- esis, clinical manifestations, diagnosis, treatment, and references. The discussions of epidemiology are particularly informative and current. The sections on pathogenesis include valuable neuropathology and critical distinctions among disorders caused by primary infection by the microorganism and those related to parainfectious and postinfectious immunological phenomena. The sections on clinical manifestations emphasize the neurological features and often are subdivided into specific neurolo- cal syndromes. Results of modern brain imaging are illustrated, and tables highlight neurological and other features. Sections on diagnosis are especially valuable and emphasize the value of polymerase chain reaction (PCR) and related means of identifying microbial nucleic acids and proteins. The discussions of treatment areespecially current and valuable.

List of contents

Viruses.- Herpes Viruses.- Myxoviruses.- Picornaviruses.- Arboviruses.- Togaviruses.- Rhabdoviruses.- Adenoviruses.- Arenaviruses.- Orthopoxviruses.- Retroviruses.- Neurological Consequences of Antiretroviral Treatment.- Papovaviruses.- Bacteria.- Bacterial Meningitis.- Focal Bacterial Infections and Parameningeal Infections.- Streptococcus pyogenes.- Bordetella pertussis.- Shigella Species.- Campylobacter Species.- Brucella Species.- Clostridium tetani.- Clostridium botulinum.- Corynebacterium diphtheriae.- Bartonella Species.- Mycobacterium tuberculosis.- Mycobacterium leprosy.- Rickettsia and Spirochetes.- Rickettsia rickettsii.- Ehrlichia and Anaplasma Species.- Borrelia burgdorferi.- Treponema pallidum.- Fungi.- Candida Species.- Cryptococcus neoformans.- Histoplasma capsulatum.- Coccidioides Species.- Phaeohyphomycoses.- Protozoa.- Protozoal Infections.- Babesia Species.- Helminths.- Helminth Infections.- Primary Immunodeficiencies.- Neurological Disease and Primary Immunodeficiency.- Basic Principles of Selective Neurological Treatments.- Basic Principles of Selective Neurological Treatments.

Summary

A major portion of all of acute child neurology involves the neurological complications of infectious diseases. However, none of the currently available excellent texts on inf- tious disease focus specifically on the neurological aspects. Drs. Neil R. Friedman and Leslie L. Barton have filled this important void with a superb, multi-authored text, addressing directly “the neurological manifestations of pediatric infectious diseases and immunodeficiency syndromes. ” The book is organized logically according to the responsible microorganisms and addresses sequentially a broad spectrum of viruses, bacteria, fungi, rickettsiae, spirochetes, mycobacteriae, and parasites, as well as cat-scratch disease and human immunodeficiency virus (HIV) infection. The chapters are consistently similar in organization and begin with an introduction that provides a synopsis and perspective. The substance of the chapters follows in sections devoted to epidemiology, pathog- esis, clinical manifestations, diagnosis, treatment, and references. The discussions of epidemiology are particularly informative and current. The sections on pathogenesis include valuable neuropathology and critical distinctions among disorders caused by primary infection by the microorganism and those related to parainfectious and postinfectious immunological phenomena. The sections on clinical manifestations emphasize the neurological features and often are subdivided into specific neurolo- cal syndromes. Results of modern brain imaging are illustrated, and tables highlight neurological and other features. Sections on diagnosis are especially valuable and emphasize the value of polymerase chain reaction (PCR) and related means of identifying microbial nucleic acids and proteins. The discussions of treatment areespecially current and valuable.

Additional text

From the reviews:

"This book addresses the neurologic emergencies of pediatric infections and immunodeficiencies in a logical, consistent fashion. … It is written for physicians in training, primary care physicians, and subspecialists. Anyone treating or aspiring to treat ill children will profit this book. … The consistent chapter organization is helpful. There is no comparable book and this one is welcome and useful. Neurologists will be better educated about infection … . As a neurologist, I will open this book frequently." (John Willis, Doody’s Review Service, September, 2008)

"The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes is a carefully devised text with extensive coverage of topic. … This book is written for physicians in training, primary health care physicians, subspecialists. … The chapters are interesting to read. … I would encourage any clinician who is actively involved in the treatment of children with neuroinfections to acquire this text as an essential part of their library." (Jo M. Wilmshurst, Clinical Infectious Diseases, Vol. 49 (1), January, 2009)

Report

From the reviews:

"This book addresses the neurologic emergencies of pediatric infections and immunodeficiencies in a logical, consistent fashion. ... It is written for physicians in training, primary care physicians, and subspecialists. Anyone treating or aspiring to treat ill children will profit this book. ... The consistent chapter organization is helpful. There is no comparable book and this one is welcome and useful. Neurologists will be better educated about infection ... . As a neurologist, I will open this book frequently." (John Willis, Doody's Review Service, September, 2008)
"The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes is a carefully devised text with extensive coverage of topic. ... This book is written for physicians in training, primary health care physicians, subspecialists. ... The chapters are interesting to read. ... I would encourage any clinician who is actively involved in the treatment of children with neuroinfections to acquire this text as an essential part of their library." (Jo M. Wilmshurst, Clinical Infectious Diseases, Vol. 49 (1), January, 2009)

Product details

• Authors: Leslie L. Barton
• Assisted by: Leslie L Barton (Editor), Leslie L. Barton (Editor), Neil R Friedman (Editor), Neil R. Friedman (Editor), Lesli L Barton (Editor), Leslie L Barton (Editor), R Friedman (Editor), R Friedman (Editor), J.J. Volpe (Foreword)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 25.10.2010
• EAN: 9781617378584
• ISBN: 978-1-61737-858-4
• No. of pages: 421
• Dimensions: 155 mm x 23 mm x 235 mm
• Weight: 663 g
• Illustrations: XVIII, 421 p. 21 illus.
• Series: Infectious Disease; Infectious Disease
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine; C, Medicine, Immunology, Neurology, Pediatrics, INTERNAL MEDICINE, Neurology & clinical neurophysiology, Infectious & contagious diseases, infectious diseases