Endocrine-Disrupting Chemicals - From Basic Research to Clinical Practice

Endocrine Disrupting Chemicals: From Basic Research to Clinical Practice is the first book that provides comprehensive coverage of the three most important themes in the field of EDC research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs. This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians' office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs.

List of contents

The Basic Biology of Endocrine Disruption.- to Endocrine-Disrupting Chemicals.- Endocrine Disruption and the Female.- Endocrine Disruption in the Male.- Endocrine-Disrupting Chemicals and the Brain.- Heavy Metals as Endocrine-Disrupting Chemicals.- Cellular Mechanisms of Endocrine Disruption.- Endocrine Disruptors, Epigenetically Induced Changes, and Transgenerational Transmission of Characters and Epigenetic States.- The Biology of EDCs in Humans.- Implications of Thyroid Hormone Signaling Through the Phosphoinositide-3 Kinase for Xenobiotic Disruption of Human Health.- Endocrine Disruption and Reproductive Outcomes in Women.- Epidemiologic Evidence on the Relationship Between Environmental Endocrine Disruptors and Male Reproductive and Developmental Health.- Human Exposures and Body Burdens of Endocrine-Disrupting Chemicals.- Implications and Mitigations of EDCs.- Policy Implications of Endocrine-Disrupting Chemicals in Humans.- Talking With Patients and the Public About Endocrine-Disrupting Chemicals.- Community Interventions to Reduce Exposure to Chemicals with Endocrine-Disrupting Properties.- What Can We Do About Endocrine-Disrupting Chemicals?.

Summary

Endocrine Disrupting Chemicals: From Basic Research to Clinical Practice is the first book that provides comprehensive coverage of the three most important themes in the field of EDC research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs. This book presents a translational approach to EDC research, spanning both basic biology and clinical applications, and provides a critical link between the laboratory and the physicians’ office. Scientists and physicians engaged in EDC studies or practice will find that this volume offers insight across all areas of EDC research, including clarifying the mechanisms for EDC effects, understanding the adverse affects of EDCs on humans and wildlife, and offering solutions to the problems created by exposures to EDCs.

Additional text

From the reviews:

"...an excellent introductory overview of endocrine disrupting chemicals. It should be of particular interest to researchers and healthcare professionals in the areas of reproductive biology and thyroid action, and endocrinologists in general." -Doody's Book Review, Weighted Numerical Score: 95 - 4 Stars

"Part of the Series Contemporary Endocrinology, this volume presents the basics, facts and policies relating to environmental chemicals endangering the endocrine system. … Of interest to environmentalists and endocrinologists." (Pediatric Endocrinology Reviews, Vol. 5 (2), December, 2007)

"This edited book ‘Endocrine Disrupting Chemicals’ is timely. … The book is divided into three distinct sections … . the amount of material covered provides a useful reference for both newcomers to the area, and the more seasoned researcher. This edited volume could serve as a text for a graduate-level course on the subject as the material in many of the chapters would serve to provide the basis for more in-depth discussions of a variety of issues." (Ralph L. Cooper, Endocrine, Vol. 32, 2007)

"This monograph belongs to well known Contemporary Endocrinology Series edited by Humana Press. … contains more than 1600 valuable references brought up to 2006. It appears useful not only for all MDs of all professions, since it brings fundamental aspects on the topic of EDCs which is touching not only health care professional, but also the general public. Careful presentation of all chapters shows also excellent editorial work which considerably helps to the reader to percept and understand individual problems discussed by the authors." (Endocrine Regulations, February, 2008)

"The book provides a firm and complete review of the current work on EDCs from basic biology to practical guides for clinicians and other professionals. … It is useful for the basic researcher … . Overall the book is a unique mix ofbasic science and practical chapters/guidebooks that focuses on chemicals that can be very harmful and cause dramatic changes in basic development and physiology. … I recommend it highly as an insightful and timely work on an important issue." (Howard C. Cromwell, General and Comparative Endocrinology, Vol. 160, 2009)

Report

From the reviews:
"...an excellent introductory overview of endocrine disrupting chemicals. It should be of particular interest to researchers and healthcare professionals in the areas of reproductive biology and thyroid action, and endocrinologists in general." -Doody's Book Review, Weighted Numerical Score: 95 - 4 Stars

"Part of the Series Contemporary Endocrinology, this volume presents the basics, facts and policies relating to environmental chemicals endangering the endocrine system. ... Of interest to environmentalists and endocrinologists." (Pediatric Endocrinology Reviews, Vol. 5 (2), December, 2007)
"This edited book 'Endocrine Disrupting Chemicals' is timely. ... The book is divided into three distinct sections ... . the amount of material covered provides a useful reference for both newcomers to the area, and the more seasoned researcher. This edited volume could serve as a text for a graduate-level course on the subject as the material in many of the chapters would serve to provide the basis for more in-depth discussions of a variety of issues." (Ralph L. Cooper, Endocrine, Vol. 32, 2007)
"This monograph belongs to well known Contemporary Endocrinology Series edited by Humana Press. ... contains more than 1600 valuable references brought up to 2006. It appears useful not only for all MDs of all professions, since it brings fundamental aspects on the topic of EDCs which is touching not only health care professional, but also the general public. Careful presentation of all chapters shows also excellent editorial work which considerably helps to the reader to percept and understand individual problems discussed by the authors." (Endocrine Regulations, February, 2008)
"The book provides a firm and complete review of the current work on EDCs from basic biology to practical guides for clinicians and other professionals. ... It is useful for the basic researcher ... . Overall the book is a unique mix ofbasic science and practical chapters/guidebooks that focuses on chemicals that can be very harmful and cause dramatic changes in basic development and physiology. ... I recommend it highly as an insightful and timely work on an important issue." (Howard C. Cromwell, General and Comparative Endocrinology, Vol. 160, 2009)

Product details

• Authors: Andrea C. Gore
• Assisted by: Andre C Gore (Editor), Andrea C Gore (Editor), Andrea C. Gore (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 25.10.2010
• EAN: 9781617377952
• ISBN: 978-1-61737-795-2
• No. of pages: 361
• Dimensions: 178 mm x 20 mm x 254 mm
• Weight: 706 g
• Illustrations: XII, 361 p. 36 illus.
• Series: Contemporary Endocrinology; Contemporary Endocrinology
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Clinical medicine; Diabetes, C, Medicine, INTERNAL MEDICINE, Endocrinology, biotechnology, Chemical Engineering, Industrial Chemistry, Industrial chemistry & chemical engineering, Industrial Chemistry/Chemical Engineering