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In Cushing's Disease, leading authorities in the field offer a thorough review of the pathogenesis, diagnostic algorithm and treatment options for this complex disease. Beginning with a fascinating history of Cushing's disease that outlines its historical significance to both endocrinology and neurosurgery, the book goes onto to cover the full range of important issues, including the molecular pathogenesis of Cushing's, anatomic pathology, the diagnosis of Cushing's syndrome, the differential of pseudo-Cushing's syndromes, hypercortisolemia, surgical removal of the corticotroph adenoma, post-operative management and assessment of remission, radiotherapeutic options, and the exciting developments in medical therapy. In addition, the book also addresses Cushing's disease in the pediatric population, given that its clinical manifestations and impact on growth can be severe; silent corticotroph adenomas as a distinct clinical entity; diagnosis and management of Cushing's disease during pregnancy, bilateral adrenalectomy, and, finally, the long-term psychological manifestations of hypercortisolemia. Comprehensive and an invaluable addition the literature, Cushing's Disease is an essential reference for enhancing diagnosis and treatment of this debilitating disorder.
List of contents
History.- Molecular Biology of Cushing's.- Pathology.- Clinical Diagnosis of Cushing's Syndrome (including Hormone Testing).- Clinical Applications of Statistical Analysis of Test Results.- Pseudo-Cushing's Syndromes.- Cyclical Cushing's.- Differential Dx of Cushing's Disease: Locating the Source of Hormone Excess.- Pituitary Imaging.- Surgical Treatment.- Postop Management and Assessment of the Cure.- Radiation Treatment.- Medical Management (including Tumor Suppressive Agents, Dopamine Agonists, etc).- Treatment of Recurrent Disease.- Pediatric Cushing's.- Silent Corticotroph Adenomas.- Cushing's and Pregnancy.- Nelson's Syndrome.- Index.
Summary
In Cushing’s Disease, leading authorities in the field offer a thorough review of the pathogenesis, diagnostic algorithm and treatment options for this complex disease. Beginning with a fascinating history of Cushing's disease that outlines its historical significance to both endocrinology and neurosurgery, the book goes onto to cover the full range of important issues, including the molecular pathogenesis of Cushing’s, anatomic pathology, the diagnosis of Cushing's syndrome, the differential of pseudo-Cushing's syndromes, hypercortisolemia, surgical removal of the corticotroph adenoma, post-operative management and assessment of remission, radiotherapeutic options, and the exciting developments in medical therapy. In addition, the book also addresses Cushing's disease in the pediatric population, given that its clinical manifestations and impact on growth can be severe; silent corticotroph adenomas as a distinct clinical entity; diagnosis and management of Cushing's disease during pregnancy, bilateral adrenalectomy, and, finally, the long-term psychological manifestations of hypercortisolemia. Comprehensive and an invaluable addition the literature, Cushing’s Disease is an essential reference for enhancing diagnosis and treatment of this debilitating disorder.
Additional text
From the reviews:
“This is an up-to-date, thorough review of the history, diagnosis, and treatment of Cushing’s disease. … the book is most suitable for practitioners involved in the diagnosis and treatment of patients with Cushing’s disease. This includes internists, endocrinologists, neurosurgeons, radiologists, and radiation oncologists. … a good review of all issues related to Cushing’s disease. It is useful to practitioners involved in the care of patients with this disorder and for those who want to learn more about the disease.” (Rebecca L. Brown, Doody’s Book Reviews, January, 2012)
“This volume reviews in 18 chapters all aspects of this disease from history and molecular biology to clinical aspects including psychosocial aspects to therapy. … Written and edited by an international team of multidisciplinary experts, this book is an asset to endocrinologists and neurosurgeons.” (Pediatric Endocrinology Reviews (PER), Vol. 9 (2), December, 2011)
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From the reviews:
"This is an up-to-date, thorough review of the history, diagnosis, and treatment of Cushing's disease. ... the book is most suitable for practitioners involved in the diagnosis and treatment of patients with Cushing's disease. This includes internists, endocrinologists, neurosurgeons, radiologists, and radiation oncologists. ... a good review of all issues related to Cushing's disease. It is useful to practitioners involved in the care of patients with this disorder and for those who want to learn more about the disease." (Rebecca L. Brown, Doody's Book Reviews, January, 2012)
"This volume reviews in 18 chapters all aspects of this disease from history and molecular biology to clinical aspects including psychosocial aspects to therapy. ... Written and edited by an international team of multidisciplinary experts, this book is an asset to endocrinologists and neurosurgeons." (Pediatric Endocrinology Reviews (PER), Vol. 9 (2), December, 2011)
