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Informationen zum Autor Noel R. Rose , MD, PhD, Professor of Pathology and of Molecular Microbiology and Immunology; Director, Center for Autoimmune Disease Research, The Johns Hopkins University Klappentext This volume of The Year in Immunology series features reviews of topics in human immunology, including B1 B cells, BCL-2 family members, Wiskott-Aldrich syndrome, reverse vaccinology, anti-b2-glycoprotein I, the role of autoimmunity In thromboangiitis obliterans (Buerger's Disease), long pentraxin PTX3 as a paradigm for humoral pattern recognition molecules, and control of inflammatory heart disease by CD4+ T cells. Inhaltsverzeichnis The proper study: preface to The Year in Immunology v Noel R. Rose The long pentraxin PTX3: a paradigm for humoral pattern recognition molecules 1 Alberto Mantovani, Sonia Valentino, Stefania Gentile, Antonio Inforzato, Barbara Bottazzi, and Cecilia Garlanda The role of autoimmunity in thromboangiitis obliterans (Buerger's disease) 15 Siva S. Ketha and Leslie T. Cooper Wiskott-Aldrich syndrome: a comprehensive review 26 Michel J. Massaad, Narayanaswamy Ramesh, and Raif S. Geha Anti-ß¿-glcoprotein I antibodies 44 Rohan Willis and Silvia S. Pierangeli Getting away with murder: how does the BCL-2 family of proteins kill with immunity? 59 Thibaud T. Ranault and Jerry E. Chipuk Control of inflammatory heart disease by CD4+ T cells 80 Jobert G. Barin and Daniela ¿iháková Human B-1 cells take the stage 97 Thomas L. Rothstein, Daniel O. Griffin, Nichol E. Holodick, Tam D. Quach, and Hiroaki Kaku Reverse vaccinology in the 21st century: improvements over the original design 115 Claudio Donati and Rino Rappuoli The National Institutes of Health Center for Human Immunology, Autoimmunity, and Inflammation: history and progress 133 Howard B. Dickler, J. Philip McCoy, Robert Nussenblatt, Shira Perl, Pamela A. Schwartzberg, John S. Tsang, Ena Wang, and Neil S. Young ...