Parameters for Pesticide Qsar and Pbpk;Pd Models for Human Risk - Assessmen

Informationen zum Autor James P. Knaak is a professor at SUNY at Buffalo. Klappentext This book will update the scientific community in the development of the parameters required by pesticide PBPK/PD models and their application in model development, simulation, and risk assessment. Zusammenfassung The metabolism of modern agrochemicals in animals, plants, and the environment have been extensively studied and reported in the literature by scientists. The results of a considerable number of these studies have been presented at National ACS, AGRO Division meetings and eventually published in the Journal of Agricultural and Food Chemistry, the ACS Symposium Series, as well as other ACS journals and books. These studies support the current registrations and use ofpesticides in the United States and worldwide. The integration of metabolism and toxicological studies in assessing human risks to pesticides is best performed using predictive physiological pharmacokinetic/pharmacodynamic and QSAR models. Physiological, biochemical, and toxicological parameters arerequired for model development and is the subject of the chapters in this book. The book will update the scientific community in the development of the parameters required by pesticide PBPK/PD models and their application in model development, simulation, and risk assessment.

Product details

• Authors: James P (EDT)/ Timchalk Knaak, James P. Knaak
• Assisted by: James P Knaak (Editor), James P. Knaak (Editor), Charles Timchalk (Editor), Timchalk Charles (Editor), Rogelio Tornero-Velez (Editor), Tornero-Velez Rogelio (Editor)
• Publisher: Oxford University Press
• Languages: English
• Product format: Hardback
• Released: 08.02.2013
• EAN: 9780841226456
• ISBN: 978-0-8412-2645-6
• No. of pages: 368
• Series: ACS Symposium Series; ACS Symposium
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Pharmacy; TECHNOLOGY & ENGINEERING / Pest Control, TECHNOLOGY & ENGINEERING / Agriculture / General, SCIENCE / Chemistry / General, chemistry, Agricultural science, Pest control, Pest control / plant diseases