Fr. 219.70

Computational Systems Biology - From Molecular Mechanisms to Disease

English · Hardback

Will be released 01.07.2013

Description

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Informationen zum Autor Associate Professor for Bioinformation Engineering at Drexel University, Philadelphia and Director of the Biocomputing Laboratory at the Coriell Institute for Medical Research Professor of Bioinformatics at the University of Heidelberg and Director of the Division of Theoretical Bioinformatics at the German Cancer Research Center (DKFZ) in Heidelberg New Approaches to Light Trapping in Solar Cell Devices discusses in detail the use of photonic and plasmonic effects for light trapping in solar cells. It compares and contrasts texturing, the current method of light-trapping design in solar cells, with emerging approaches employing photonic and plasmonic phenomena. These new light trapping methods reduce the amount of absorber required in a solar cell, promising significant cost reduction and efficiency. This book highlights potential advantages of photonics and plasmonics and describes design optimization using computer modeling of these approaches. Its discussion of ultimate efficiency possibilities in solar cells is grounded in a review of the Shockley-Queisser analysis; this includes an in-depth examination of recent analyses building on that seminal work. Zusammenfassung Discusses the experimental and theoretical foundations of the function of biological systems at the molecular! cellular or organismal level over temporal and spatial scales! as systems biology advances to provide clinical solutions to complex medical problems.

List of contents

Introducing Computational Systems Biology; Protein Interactions, Stability and Regulation; Transcriptional control; Introduction to Computational Models of Biochemical Reaction Networks; Biological Foundations of Signal Transduction and Aberrations in Disease; A discrete approach to top-down modeling of biochemical networks; Reconstruction of metabolic network from genome information and its structural and functional analysis; Gene networks: estimation, modeling and simulation; Standards, platforms and tools; Computational models for circadian rhythms: Deterministic versus stochastic approaches; Integrated imaging informatics; Imaging and Modeling of complex tumor formation; Imaging to help decipher an model higher orders of complexity; Multistability and multicellularity: cell fates as high-dimensional attractors of gene regulatory networks; Whole Cell Modeling; Databases for Systems Biology; Systems Biology of the Microbiome; Systems Immunology; Applying systems biology to understand the immune response to infection and vaccination; Aging and Systems Biology; From Cardiac Mitochondria to Systems Physiology; Cancer Systems Biology; Systems Medicine, Drug Biology and Interventions; Towards a blueprint of an entire organism

Report

".revised and updated to include the latest advances in cancer, aging, and development modeling research. The first chapter introduces the field and reviews the content to follow, while the ensuing six chapters lay the foundations of modeling networks, systems analysis, biochemistry, and signal transduction underlying the systems approach,." --ProtoView.com, April 2014

Product details

Authors Roland Eils, KRIETE, Andres Kriete, Andres (EDT)/ Eils Kriete
Assisted by Roland Eils (Editor), Roland (Theoretical Bioinformatics Eils (Editor), Eils Roland (Editor), Andres Kriete (Editor), Andres (Drexel University Kriete (Editor), Kriete Andres (Editor)
Publisher Academic Press London
 
Languages English
Product format Hardback
Release 01.07.2013, delayed
 
EAN 9780124059269
ISBN 978-0-12-405926-9
No. of pages 464
Subjects Natural sciences, medicine, IT, technology > IT, data processing > IT

SCIENCE / Life Sciences / Biology, COMPUTERS / Computer Simulation, Biology, life sciences, Computer modelling & simulation, Computer modelling and simulation

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