Fatal Attractions: Protein Aggregates in Neurodegenerative Disorders

In this volume are contributions based on a meeting arranged by the WHO and the Fondation IPSEN. The scientists focus on neurodegenerative disorders like Alzheimer's Disease, Chromosome 17-Linked Dementia, Parkinson's Disease and disorders with tauopathies.

List of contents

The Role of ?-Synuclein in Parkinson's Disease: A Biophysical Analogy to A? and Alzheimer's Disease.- Purification of Lewy Bodies and Identification of ? -Synuclein as a Major Component of Lewy Bodies.- Mutational Analysis of Tau in Chromosome 17-Linked Dementia.- Missense and Splice Site Mutations in Tau Associated with FTDP-17: Multiple Pathogenic Mechanisms.- Tau Mutations: Genetics and Pathogenetic Mechanisms.- Tauopathies and ?-Synucleinopathies.- Distinct Tau Gene Mutations Induce Specific Dysfunctions/Toxic Properties in Tau Proteins Associated with Specific FTDP-17 Phenotypes.- Neurodegenerative Disorders with Tauopathies: Mad Tau Diseases?.- Tau Protein: Role in Intracellular Traffic and Development of Cell Polarity.

Product details

• Assisted by: L. Buee (Editor), L. Buée (Editor), L Buee et al (Editor), Y. Christen (Editor), V. M. -Y. Lee (Editor), V.M.-Y. Lee (Editor), Q Trojanowski (Editor), J Q Trojanowski (Editor), J. Q. Trojanowski (Editor), J.Q. Trojanowski (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 11.10.2010
• EAN: 9783642086496
• ISBN: 978-3-642-08649-6
• No. of pages: 140
• Dimensions: 155 mm x 8 mm x 235 mm
• Weight: 248 g
• Illustrations: XII, 140 p.
• Series: Research and Perspectives in Alzheimer's Disease; Research and Perspectives in Alzheimer's Disease
• Subject: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine