Molecular Biology of Neuropsychiatric Disorders

It is generally accepted that neuropsychiatric disorders have a biological basis. Pathological changes leading to illness have been confirmed for Alzheimer's (amyloid plaques) and Parkinson's disease (loss of dopaminergic transmission) and are the foundation for studies on the molecular biology of these disorders. For other neuropsychiatric disorders, in particular for schizophrenic and affective disorders, molecular causes appear to be more complex and therefore remain hypothetical, despite decades of research. Changes in a number of neuronal pathways and structures have been reported to be associated with these disorders and are currently under extensive investigation. The present volume reviews recent knowledge with emphasis on ongoing research findings. Current hypotheses based on these findings are described and discussed.

List of contents

Decoding the Genetics and Underlying Mechanisms of Mood Disorders Sevilla D. Detera-Wadleigh and Takeo Yoshikawa.- Dissecting the Molecular Causes of Schizophrenia.- Autism Spectrum Disorders.- Molecular Genetics of ADHD.- The Genetics of Anxiety Disorders.- Molecular Biology of Addiction and Substance Dependence.- Neurobiology of Suicide.- Molecular Genetics of Alzheimer's Disease.- Molecular Biology of Parkinson's Disease.

Summary

It is generally accepted that neuropsychiatric disorders have a biological basis. Pathological changes leading to illness have been confirmed for Alzheimer’s (amyloid plaques) and Parkinson’s disease (loss of dopaminergic transmission) and are the foundation for studies on the molecular biology of these disorders. For other neuropsychiatric disorders, in particular for schizophrenic and affective disorders, molecular causes appear to be more complex and therefore remain hypothetical, despite decades of research. Changes in a number of neuronal pathways and structures have been reported to be associated with these disorders and are currently under extensive investigation. The present volume reviews recent knowledge with emphasis on ongoing research findings. Current hypotheses based on these findings are described and discussed.

Product details

• Assisted by: Diete B Wildenauer (Editor), Dieter B Wildenauer (Editor), Dieter B. Wildenauer (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 08.12.2010
• EAN: 9783642099069
• ISBN: 978-3-642-09906-9
• No. of pages: 294
• Weight: 468 g
• Illustrations: XIII, 294 p.
• Series: Nucleic Acids and Molecular Biology; Nucleic Acids and Molecular Biology
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine; Biochemie, C, Neurologie und klinische Neurophysiologie, Medical research, Biopsychologie, Physiologische Psychologie, Neuropsychologie, Life Sciences, Neurology, Medizinische Forschung, biochemistry, molecular biology, Neurology & clinical neurophysiology, Physiological & neuro-psychology, biopsychology, neuropsychology, Biomedical and Life Sciences, Biochemistry, general, Zoology, Biomedical Research, Molecular Medicine, Neurobiology