Fr. 69.00

Function and Control of the Spx-Family of Proteins Within the Bacterial Stress Response

English · Paperback / Softback

Shipping usually within 1 to 2 weeks (title will be printed to order)

Description

Read more

This SpringerBrief on Spx reviews the investigations that led to the discovery of Spx and its orthologs and ties together the results of various studies that have explored the function and control of spx in Gram-positive organisms. Spx of Bacillus subtilis has been extensively studied, but very little has been published about it. This book incorporates a number of studies that have been conducted in other Gram positive bacteria, which examined the role of Spx orthologs in stress response, bacterial development and virulence.


The book contains an overview that will introduce the protein and its orthologous forms, its association with RNA polymerase, the species of Gram-positive bacteria in which it is found, and the conditions in which it is abundant and active. Spx is a member of a large group of proteins belonging to the ArsC/Spx protein family, so the review touches upon the bioinformatic support for the protein family composition and its meaning with regard to protein structure/function.

List of contents

Introduction.- An overview of Spx.- Regulation of the stress response in Gram-positive bacteria.- Expression of spx is affected by multiple stress stimuli.- Post-transcriptional control of Spx: Redox-dependent activation.- Post-transcriptional control of Spx: Regulated proteolysis.- Targets of Spx-dependent transcriptional activation.- Spx function and bacterial virulence.- Questions and future directions.

Summary

This SpringerBrief on Spx reviews the investigations that led to the discovery of Spx and its orthologs and ties together the results of various studies that have explored the function and control of spx in Gram-positive organisms.  Spx of Bacillus subtilis has been extensively studied, but very little has been published about it. This book incorporates a number of studies that have been conducted in other Gram positive bacteria, which examined the role of Spx orthologs in stress response, bacterial development and virulence.
 
 
The book contains an overview that will introduce the protein and its orthologous forms, its association with RNA polymerase, the species of Gram-positive bacteria in which it is found, and the conditions in which it is abundant and active. Spx is a member of a large group of proteins belonging to the ArsC/Spx protein family, so the review touches upon the bioinformatic support for the protein family composition and its meaning with regard to protein structure/function. ​ 

Product details

Authors Skye Barendt, Peter Zuber
Publisher Springer, Berlin
 
Languages English
Product format Paperback / Softback
Released 30.01.2013
 
EAN 9781461469247
ISBN 978-1-4614-6924-7
No. of pages 49
Dimensions 152 mm x 239 mm x 6 mm
Illustrations V, 49 p. 6 illus. in color.
Series SpringerBriefs in Molecular Science
SpringerBriefs in Microbiology
SpringerBriefs in Molecular Science
SpringerBriefs in Microbiology
Subject Natural sciences, medicine, IT, technology > Medicine > Clinical medicine

Customer reviews

No reviews have been written for this item yet. Write the first review and be helpful to other users when they decide on a purchase.

Write a review

Thumbs up or thumbs down? Write your own review.

For messages to CeDe.ch please use the contact form.

The input fields marked * are obligatory

By submitting this form you agree to our data privacy statement.