Blood-Brain Barrier Permeability Changes after Subarachnoid Haemorrhage: An Update - Clinical Implications, Experimental Findings, Challenges and Future Directions

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List of contents

The Concept of the BBB: A Historical Perspective.- Anatomy of the BBB.- Pathophysiology of BBB.- Brain Oedema.- Breakdown of the BBB.- BBB Dysfunction after SAH.- Clinical Monitoring.- Neuroradiological Findings of BBB Dysfunction after SAH.- Computerised Tomography and Magnetic Resonance SPECT and PET.- Experimental Data.- Literature Review of BBB Dysfunction after Experimental SAH.- Qualitative Assessments of BBB Dysfunction after SAH.- Quantitative Assessments of BBB Dysfunction.- Time Course of BBB Dysfunction after SAH.- Additional Pathophysiological Changes after SAH.- Strategies for Pharmacological Intervention.- Hydroxyl Radical Scavenger AVS.- Glutamate Antagonist Felbamate.- Calpain Inhibitor II.- Challenges and Future Direction.- Advances in Cerebrovascular Pathophysiology.- Gene Therapy.- References.

Product details

• Authors: Antonio Germano, Antonio F Germano, Antonio F. Germano, Francesco Tomasello
• Publisher: Springer, Wien
• Languages: English
• Product format: Paperback / Softback
• Released: 25.01.2013
• EAN: 9783709172506
• ISBN: 978-3-7091-7250-6
• No. of pages: 130
• Weight: 237 g
• Illustrations: X, 130 p.
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine; C, neurosurgery, Medicine, Neurology, Pathology, Neuroscience, Neurosciences, Pharmacology, Pharmacy, Health Sciences, Pharmacology/Toxicology, Pharmacy / dispensing