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Informationen zum Autor Gil Wolfe is the editor of Myasthenia Gravis and Related Disorders I: 12th International Conference, Volume 1274, published by Wiley. Emma Ciafalonia is the editor of Myasthenia Gravis and Related Disorders I: 12th International Conference, Volume 1274, published by Wiley. Klappentext Myasthenia gravis (MG), an acquired immune syndrome affecting proteins at the neuromuscular junction, causes significant muscular functional impairment and can compromise patients' quality of life, including fatigue, disability, and increased mortality rates. Continued efforts in the last decades have begun to produce significant progress in our understanding of this rare condition, yet considerable challenges remain for improving diagnosis and developing effective treatments for MG. The present volume comprises papers stemming from the "12th International Conference on Myasthenia Gravis and Related Disorders," held May 21-23, 2012 at the New York Academy of Sciences in New York City. The papers collected in this first of two Annals volumes highlight some of the key developments in neuroscience and immunology in MG and related syndromes presented at the conference, including structure and function of the neuromuscular junction, advances in immunology and their relationship to myasthenia gravis, clinical and laboratory developments, outcome measurements and clinical trial development, and animal models of neuromuscular junction disease. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit: http: //ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http: //www.nyas.org/MemberCenter/Join.aspx for more information on becoming a member. Zusammenfassung Myasthenia gravis (MG)! an acquired immune syndrome affecting proteins at the neuromuscular junction! causes significant muscular functional impairment and can compromise patients quality of life! including fatigue! disability! and increased mortality rates. Inhaltsverzeichnis Neuromuscular Junction Physiology and Pathophysiology Acetylcholine Receptor Structure Immunopathogenesis of Myasthenia Gravis Animal Models of Myasthenia Gravis for Preclinical Evaluation Epidemiology and Genetics of Myasthenia Gravis Clinical Presentations of Myasthenia Gravis Ocular Myasthenia Thymoma-Associated Myasthenia Gravis Electrodiagnosis of Neuromuscular Junction Disorders Autoantibody Testing in the Diagnosis and Management of Autoimmune Disorders of Neuromuscular Transmission and Related Diseases Treatment of Myasthenia Gravis Neurocritical Care of Myasthenic Crisis Thymectomy for Non-thymomatous Myasthenia Gravis Lambert-Eaton Syndrome Acquired Neuromyotonia Congenital Myasthenic Syndromes Toxic Neuromuscular Transmission Disorders Predictors of Psychological Health in Myasthenia Gravis Myasthenia Gravis: Classification and Outcome Measurements Emerging Therapeutics for Myasthenia Gravis Clinical Trial Design for Myasthenia Gravis ...