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This is a comprehensive and up-to-date guide to the diagnosis, clinical features and management of inherited disorders conferring cancer susceptibility. It is fully updated with much molecular, screening and management information. It covers risk analysis and genetic counselling for individuals with a family history of cancer. It also discusses predictive testing and the organisation of the cancer genetics service. There is information about the genes causing Mendelian cancer predisposing conditions and their mechanism of action. It aims to provide such details in a practical format for geneticists and clinicians in all disciplines.
List of contents
1. Central Nervous System.- 2. Eye.- 3. Cardiorespiratory System and Thorax.- 4. Endocrine System.- 5. Gastrointestinal System.- 6. Reproductive System.- 7. Urinary System.- 8. Blood and Lymph.- 9. Musculoskeletal System.- 10. Skin.- 11. Inherited Cancer-Predisposing Syndromes.
Summary
This is a comprehensive and up-to-date guide to the diagnosis, clinical features and management of inherited disorders conferring cancer susceptibility. It is fully updated with much molecular, screening and management information. It covers risk analysis and genetic counselling for individuals with a family history of cancer. It also discusses predictive testing and the organisation of the cancer genetics service. There is information about the genes causing Mendelian cancer predisposing conditions and their mechanism of action. It aims to provide such details in a practical format for geneticists and clinicians in all disciplines.
Additional text
“Cancer genetics is an established part of clinical
medicine, and this development can be followed through the different editions
of this classical textbook. … For the clinical specialist in genetics or any
other specialty meeting cancer patients and their family members, or for the
resident, this textbook is useful as a first source … . I will strongly
recommend this book to those who meet patients who ask questions about the
heritability of the cancer in their family … .” (U. Kristoffersson, European
Journal of Human Genetics, 2015)
Report
"Cancer genetics is an established part of clinical medicine, and this development can be followed through the different editions of this classical textbook. ... For the clinical specialist in genetics or any other specialty meeting cancer patients and their family members, or for the resident, this textbook is useful as a first source ... . I will strongly recommend this book to those who meet patients who ask questions about the heritability of the cancer in their family ... ." (U. Kristoffersson, European Journal of Human Genetics, 2015)
