Immunoassay Handbook - Theory Applications of Ligand Binding, Elisa Related Techniques

Informationen zum Autor David Wild is a healthcare industry veteran, with experience in biotechnology, pharmaceuticals, medical devices and immunodiagnostics, which remains his passion. He worked for Amersham, Eastman-Kodak, Johnson & Johnson, and Bristol-Myers Squibb, and consulted for diagnostics and biotechnology companies. He led research and development programs, design and construction of chemical and biotechnology plants, and integration of acquired companies. Director-level positions included Research and Development, Design Engineering, Operations and Strategy, for billion dollar businesses. He retired from full-time work in 2012 to focus on his role as Editor of The Immunoassay Handbook, and advises on product development, manufacturing and marketing. Klappentext 4th edition. Zusammenfassung Provides a guide to the science, technology and applications of ELISA and other immunoassays, including a wealth of practical advice. This title encompasses a range of methods and gives an insight into the developments and applications in clinical and veterinary practice and in pharmaceutical and life science research. Inhaltsverzeichnis Part 1 IMMUNOASSAY FUNDAMENTALS 1.1 How to use this book 1.2 Immunoassays for beginners 1.3 Immunoassay performance measures  Part 2 IMMUNOASSAY CONFIGURATIONS 2.1 Competitive and immunometric assays (including ELISA) 2.2 Non-competitive immunoassays for small molecules 2.3 Homogenous immunoassays 2.4 Lateral flow immunoassay devices 2.5 Ambient analyte immunoassay 2.6 Free analyte immunoassay 2.7 Qualitative immunoassays 2.8 Immunoassays for the detection or quantification of antibodies 2.9 Microsphere-based Multiplex Immunoassays: Development and Applications using Luminex xMAP Technology 2.10 Lab on a chip 2.11 Immunological Biosensors 2.12 SPR 2.13 Single Molecule Array   Part 3 IMMUNOASSAY COMPONENTS 3.1 Antibodies 3.2 Signal generation systems 3.3 Solid-phase and other separation systems 3.4 Conjugation methods 3.5 Standardisation and calibration 3.6 Calibration curve-fitting   Part 4 RELATED TECHNIQUES 4.1 Foundations of immunochemistry 4.2 Immunohistochemistry and immunofluorescence   Part 5 IMMUNOASSAY DEVELOPMENT 5.1 Practical guide to ELISA development 5.2 Performance evaluation and validation 5.3 Interferences in immunoassay 5.4 Immunoassay development in industry  Part 6 IMMUNOASSAY IMPLEMENTATION 6.1 Subject preparation, sample collection and handling 6.2 Laboratory quality assurance 6.3 Point-of-care testing 6.4 Choosing an automated immunoassay system 6.5 Troubleshooting guide  Part 7 IMMUNOASSAY PRODUCT TECHNOLOGY 7.1 Introduction to product technology 7.2 Market trends 7.3 Lateral Flow and Consumer Diagnostics 7.4 Clearblue 7.5 TRIAGE 7.6 Stratus CS 7.7 IMx 7.8 AxSYM 7.9 Architect 7.10 Advia CENTAUR 7.11 IMMULITE and IMMULITE 1000 7.12 IMMULITE 2000 and IMMULITE 2000 Xpi 7.13 Eci 7.14 Vitros Clin chem 7.15 Access 2 7.16 Dxl 600 and 800 7.17 Elecsys 7.18 PRISM 7.19 Phadia systems  Part 8 IMMUNOASSAY APPLICATIONS OTHER THAN CLINICAL CHEMISTRY 8.1 Immunoassay applications in veterinary diagnostics 8.2 Immunoassays in the pharmaceutical industry  Part 9 IMMUNOASSAY CLINICAL APPLICATIONS (HUMAN) 9.1 Clinical concepts 9.2 Thyroid 9.3 The adrenal cortex 9.4 Bone metabolism 9.5 Infertility 9.6 In vitro fertilization and embryo transfer 9.7 Hirsutism and virilization in the female 9.8 Pregnancy 9.9 Growth and growth hormone deficiency 9.10 Diabetes mellitus 9.11 Hematology 9.12 Cardiac markers 9.13 Cancer markers 9.14 Allergy 9.15 Autoimmune diseases 9.16 GI Tract 9.17 Hepatitis 9.18 HIV 9.19 Other viral diseases (excl HIV and Hepatitis) 9.20 Other bacterial diseases 9.21 Fungal and parasitic...

List of contents

Part 1 IMMUNOASSAY FUNDAMENTALS
1.1 How to use this book
1.2 Immunoassays for beginners
1.3 Immunoassay performance measures
Part 2 IMMUNOASSAY CONFIGURATIONS
2.1 Competitive and immunometric assays (including ELISA)
2.2 Non-competitive immunoassays for small molecules
2.3 Homogenous immunoassays
2.4 Lateral flow immunoassay devices
2.5 Ambient analyte immunoassay
2.6 Free analyte immunoassay
2.7 Qualitative immunoassays
2.8 Immunoassays for the detection or quantification of antibodies
2.9 Microsphere-based Multiplex Immunoassays: Development and Applications using Luminex xMAP Technology
2.10 Lab on a chip
2.11 Immunological Biosensors
2.12 SPR
2.13 Single Molecule Array
Part 3 IMMUNOASSAY COMPONENTS
3.1 Antibodies
3.2 Signal generation systems
3.3 Solid-phase and other separation systems
3.4 Conjugation methods
3.5 Standardisation and calibration
3.6 Calibration curve-fitting
Part 4 RELATED TECHNIQUES
4.1 Foundations of immunochemistry
4.2 Immunohistochemistry and immunofluorescence
Part 5 IMMUNOASSAY DEVELOPMENT
5.1 Practical guide to ELISA development
5.2 Performance evaluation and validation
5.3 Interferences in immunoassay
5.4 Immunoassay development in industry
Part 6 IMMUNOASSAY IMPLEMENTATION
6.1 Subject preparation, sample collection and handling
6.2 Laboratory quality assurance
6.3 Point-of-care testing
6.4 Choosing an automated immunoassay system
6.5 Troubleshooting guide
Part 7 IMMUNOASSAY PRODUCT TECHNOLOGY
7.1 Introduction to product technology
7.2 Market trends
7.3 Lateral Flow and Consumer Diagnostics
7.4 Clearblue
7.5 TRIAGE
7.6 Stratus CS
7.7 IMx
7.8 AxSYM
7.9 Architect
7.10 Advia CENTAUR
7.11 IMMULITE and IMMULITE 1000
7.12 IMMULITE 2000 and IMMULITE 2000 Xpi
7.13 Eci
7.14 Vitros Clin chem
7.15 Access 2
7.16 Dxl 600 and 800
7.17 Elecsys
7.18 PRISM
7.19 Phadia systems
Part 8 IMMUNOASSAY APPLICATIONS OTHER THAN CLINICAL CHEMISTRY
8.1 Immunoassay applications in veterinary diagnostics
8.2 Immunoassays in the pharmaceutical industry
Part 9 IMMUNOASSAY CLINICAL APPLICATIONS (HUMAN)
9.1 Clinical concepts
9.2 Thyroid
9.3 The adrenal cortex
9.4 Bone metabolism
9.5 Infertility
9.6 In vitro fertilization and embryo transfer
9.7 Hirsutism and virilization in the female
9.8 Pregnancy
9.9 Growth and growth hormone deficiency
9.10 Diabetes mellitus
9.11 Hematology
9.12 Cardiac markers
9.13 Cancer markers
9.14 Allergy
9.15 Autoimmune diseases
9.16 GI Tract
9.17 Hepatitis
9.18 HIV
9.19 Other viral diseases (excl HIV and Hepatitis)
9.20 Other bacterial diseases
9.21 Fungal and parasitic diseases
9.22 Therapeutic drug monitoring
9.23 Drugs of abuse

Report

"The beauty of this book is that it covers the whole field of immunoassay from reagents to method development, interferences and applications.The fourth edition does not disappoint. It is an essential reference manual for staff using immunoassays and to students in the field of laboratory medicine and other science disciplines." --Annals of Clinical Biochemistry, November 2013
"The book starts out very basic with principles of immunoassays ('immunoassays for beginners') and builds progressively to discuss immunoassay components, configurations, development, implementation, product technology, applications other than clinical chemistry, and concludes with 23 chapters on clinical applications to human disease.This is the single 'go-to' book for any questions regarding immunoassays. If this is an area of interest for you, you must have this edition." --Doody.com, November 2013
"Editors Wild, John, Sheehan, Binder, and He present this handbook on the highly sensitive technique of immunoassay.Equations, figures, and real-world examples are used to clarify mechanisms and analysis. The range of detail makes it appropriate as both a pedagogical resource and a reference for immunology labs." --Reference and Research Book News, October 2013
"...it must be stated that there is much of value in the volume [2nd Ed.]. It is a useful and informative addition to any scientific library." --Robert F. Ritchie, Foundation for Blood Research, Scarborough, USA

Product details

• Authors: David Wild, David (Healthcare Industry Consultant Wild, David Geoffrey Wild, David Geoffrey (EDT) Wild, WILD DAVID GEOFFREY
• Assisted by: David Wild (Editor), David (Healthcare Industry Consultant Wild (Editor), David Geoffrey Wild (Editor), Wild David (Editor)
• Publisher: ELSEVIER SCIENCE BV
• Languages: English
• Product format: Hardback
• Released: 31.01.2013
• EAN: 9780080970370
• ISBN: 978-0-08-097037-0
• No. of pages: 1036
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Clinical medicine; SCIENCE / Life Sciences / Biochemistry, biochemistry, Biochemical immunology