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The study of complex physiological and metabolic aspects of human health can be powerfully enhanced by the use of user-friendly simulation software. This book and CD-ROM integrate the use of STELLA software into the teaching of health, nutrition and physiology, and can be used on their own in nutrition and physiology courses, or can serve as a supplement to introduce the role that simulation modeling can play. Dynamic Modeling in the Health Sciences presents key subjects ranging from the theory of metabolic control to weight regulation to bone metabolism, and gives readers the tools to simulate these dynamic processes with STELLAÊha software. Topics include methods for simulation of gene expression, a multi-stage model of tumor development, theories of aging, circadian rhythms and physiological time, and a model for managing weight loss and preventing obesity.
List of contents
Discoveries with a Computer.
- How to Create STELLA Models to Solve Equations.
- How the Nernst Equation Can Become aModel.
- Rates of Change.
- The Steady State.
- Allometric Equations for Model Building.
- Primer on Biodynamics and Gene Expression.
- Physiological Time.
- Energy and Work.
- The Human Thermostat.
- Dietary Polyunsaturated Fats and Your Cell Membranes.
- Responses to Nutrients.
- Symmetry of Human Growth and Aging.
- A Stochastic Model of Senescence and Demise.
- Mortality and Risk for Chronic Disease.
- Kinetic Genetics: Compartmental Models of Gene Expression.
- From Genotype to Phenotype.
- The Plateau Principle.
- Compartmental Models in Metabolic Studies: Vitamin C.
- Circadian Rhythms.
- Diet Composition and Fat Balance.
- Human Cholesterol Dynamics.
- Stochastic Model of Bone Remodeling and Osteoporosis.
- Positive and Negative Feedback: Insulin and the Use of Fatty Acids and Glucose for Energy.
- A Multistage Model of Tumor Progression.
- The Biokinetic Database.
