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Informationen zum Autor Lothar Kanz is a Professor in Hematology, Oncology und Immunology at the University of Tübingen, Tübingen, Germany. Claudia Lengerke, M.D. is Head of the Laboratory for Developmental Biology, Division of Hematology and Oncology, at the University of Tuebingen Medical Center. Willem E. Fibbe is a Professor at Leiden University Medical Center, Leiden, the Netherlands. John E. Dick, PhD is a Senior Scientist in the Division of Cellular & Molecular Biology at Toronto General Research Institute (TGRI), University of Toronto, Toronto, Ontario, Canada. Klappentext "The Eight[h] International Conference and Workshop on Hematopoietic Stem Cells was held on September 22-24, 2011 in T'ubingen, Germany"--Pref. Zusammenfassung This volume stems from the eighth international symposium and workshop entitled "Hematopoietic Stem Cells VIII" held hosted by the University of Tuebingen! Germany in the fall of 2011. The meeting was designed to bring ~30 leading scientists together to discuss the state-of-the-art in the field of hematopoietic stem cells. Inhaltsverzeichnis Preface for Hematopoietic Stem Cells VIII vii Claudia Lengerke, Willem E. Fibbe, John E. Dick, and Lothar Kanz Basic aspects of stem cell biology Epigenetic differences between sister chromatids? 1 Peter M. Lansdorp, Ester Falconer, Jiang Tao, Julie Brind'Amour, and Ulrike Naumann Reprogramming cell fates: insights from combinatorial approaches 7 Carlos-Filipe Pereira, Ihor R. Lemischka, and Kateri Moore Molecular live cell bioimaging in stem cell research 18 Max Endele and Timm Schroeder The role of telomere shortening in somatic stem cells and tissue aging: lessons from telomerase model systems 28 Stefan Tümpel and K. Lenhard Rudolph Hematopoietic stem cell development and molecular regulation In vivo divisional tracking of hematopoietic stem cells 40 Hitoshi Takizawa and Markus G. Manz Caudal genes in blood development and leukemia 47 Claudia Lengerke and George Q. Daley Hematopoietic stem cells are regulated by Cripto, as an intermediary of HIF-1¿ in the hypoxic bone marrow niche 55 Kenichi Miharada, Göran Karlsson, Matilda Rehn, Emma Rörby, Kavitha Siva, Jörg Cammenga, and Stefan Karlsson G protein-coupled receptor crosstalk and signaling in hematopoietic stem and progenitor cells 63 Robert Möhle and Adriana C. Drost Molecular and functional characterization of early human hematopoiesis 68 Elisa Laurenti and John E. Dick Role of N-cadherin in the regulation of hematopoietic stem cells in the bone marrow niche 72 Fumio Arai, Kentaro Hosokawa, Hirofumi Toyama, Yoshiko Matsumoto, and Toshio Suda Differential requirements for Wnt and Notch signaling in hematopoietic versus thymic niches 78 Paul P.C. Roozen, Martijn H. Brugman, and Frank J.T. Staal Phenotypic and functional heterogeneity of human bone marrow- and amnion-derived MSC subsets 94 Kavitha Sivasubramaniyan, Daniela Lehnen, Roshanak Ghazanfari, Malgorzata Sobiesiak, Abhishek Harichandan, Elisabeth Mortha, Neli Petkova, Sabrina Grimm, Flavianna Cerabona, Peter de Zwart, Harald Abele, Wilhelm K. Aicher, Christoph Faul, Lothar Kanz, and Hans-Jörg Bühring Safety and efficacy of mesenchymal stromal cell therapy in autoimmune disorders 107 Maria Ester Bernardo and Willem E. Fibbe Stem cells and cancer TIM-3 as a therapeutic target for malignant stem cells in acute myelogenous leukemia 118 Yoshikane Kikushige and Koichi Akashi Zebrafish xenografts as a tool for in vivo studies on human cancer 124 Martina Konantz, Tugce B. Balci, Udo F. Hartwig, Graham Dellaire, Maya C. André, Jason N. Berman, and Cl...
