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Informationen zum Autor Giovanni Cizza and Kristina I. Rother are the authors of The Brain and Obesity, Volume 1264, published by Wiley. Klappentext "It is a great pleasure to introduce the Brain and Obesity Lecture Series in this issue of Annals of the New York Academy of Sciences. These lectures were initiated in 2006 when the Intramural Center for Obesity was about to open at the National Institutes of Health (NIH) Clinical Center, a state-of-the art facility that includes a 21-bed inpatient facility and three metabolic chambers and other equipment for studies on phenotyping subjects with obesity. An interdisciplinary group of clinical investigators was recruited that included endocrinologists, nutritionists, geneticists, exercise physiologists, and neuropsychologists. The fact that the Intramural Center for Obesity was part of the NIH Clinical Center, a 240-bed facility completely devoted to clinical research, offered a valuable opportunity for collaboration and cross-fertilization within clinical research and with translational and basic research. We shared with other colleagues, mostly in the field of neurosciences, the conviction that the brain plays a pivotal role in obesity. This notion, largely accepted today, was quite controversial at the time. Rather, it was thought that obesity was a problem of eating too much and exercising too little. Without challenging this obvious tenet--derived from the law of thermodynamics--we thought that there was much more to it. Another commonly held notion was that "a calorie, is a calorie, is a calorie," a notion that has now been revisited. The Brain and Obesity Lecture Series started us on a journey of exploration, a search for ongoing work based on the idea that the brain had something to do with the development of obesity. In the following five years, there were a total of 16 lectures. On March 22, 2012, ten of the original speakers, or members of their respective teams, returned to the NIH Clinical Center for a final round of talks and discussions"--P. vii. Zusammenfassung The prevalence of obesity has dramatically increased over the last 25 years. In the United States! it is estimated that two-thirds of the population is either overweight or obese. This increase will undoubtedly continue to have profound medical! economic! and psychosocial consequences. Inhaltsverzeichnis The Brain and Obesity Lectures Series - the beginning of a new field? Giovanni Cizza Kristina I. Rother vii Conjectures on some curious connections among social status, calorie restriction, hunger, fatness, and longevity Kathryn A. Kaiser Daniel L: Smith David B. Allison 1 Role of the blood-brain barrier in the evolution of feeding and cognition William A. Banks 13 The hypothalamic-pituitary-adrenal axis and sex hormones in chronic stress and obesity: pathophysiological and clinical aspects Renato Pasquali 20 Food reward in the obese and after weight loss induced by calorie restriction and bariatric surgery Hans-Rudolf Berthoud Huiyuan Zheng Andrew C. Shin 36 Brain-derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health Sarah M. Rothman Kathleen J. Griffioen Ruiqian Wan Mark P. Mattson 49 Leptin action on nonneuronal cells in the CNS: potential clinical applications Weihong Pan Hung Hsuchou Bhavaani Jayaram Reas S. Khan Eagle Yi-Kung Huang Xiaojun Wu Chu Chen Abba J. Kastin 64 Brain orexin promotes obesity resistance Catherine Kotz Joshua Nixon Tammy Butterick Claudio Perez-Leighton Jennifer Teske Charles Billington 72 Visceral adipose tissue: emerging role of gluco- and mineralocorticoid hormones in the setting of cardiometabolic alterations Marco Boscaro Gilberta Giacchetti Vanessa Ronconi 87 The circadian clock transcriptional complex: metabolic feedback intersects with epigenetic control Selma Masri Loredana Zocchi Sayako Katada Eugenio M...
