Immunology At a Glance

Informationen zum Autor Professor John H L Playfair, MB BChir PhD DSc, Emeritus Professor of Immunology, University College London, UK. Professor Benjamin M Chain BA, PhD, FRCPath, Professor of Immunology and Head of Department at the Windeyer Institute of Medical Sciences, University College London, UK. Klappentext Immunology at a Glance provides a user-friendly overview of the body's defence mechanisms. Ideal from day one of a medical, biomedical or life science course, the text begins with a basic overview of both adaptive and innate immunity, before progressing to applied immunological concepts, which look at what happens when things go wrong, and how, in clinical medicine, each body system can be affected by immunity. Each double-page spread corresponds to a typical lecture and diagrammatically summarises core concepts in immunology, through accessible schematic diagrams on left-hand pages, with key points concisely summarised on the right-hand page. There are also self-assessment essay questions so you can test your knowledge. New for this 10th edition: Thoroughly updated and reorganised chapters offer greater clarity and easier understanding for those new to the subject New chapters on cytokine receptors and 'Immunology in the Laboratory' A completely re-written section on autoimmunity A brand new companion website featuring self-assessment questions and PowerPoint slides of images from the book, ideal for teaching and revision at www.ataglanceseries.com/immunology Immunology at a Glance is the ideal companion for anyone about to start a new course in immunology and will appeal to medical and biomedical science students. Perfect for exam preparation, it provides the concepts and frameworks you need to succeed in your exam. Zusammenfassung Immunology at a Glance provides a user-friendly overview of the body s defence mechanisms. Inhaltsverzeichnis Preface 6 Acknowledgements 6 Note on the tenth edition 6 How to use this book 7 Further reading 7 List of abbreviations 8 Immunity 1 The scope of immunology 10 2 Innate and adaptive immune mechanisms 12 3 Recognition and receptors: the keys to immunity 14 4 Cells involved in immunity: the haemopoietic system 16 Innate immunity 5 Receptors of the innate immune system 18 6 Complement 20 7 Acute inflammation 22 8 Phagocytic cells and the reticuloendothelial system 24 9 Phagocytosis 26 Adaptive immunity (i) The molecular basis 10 Evolution of recognition molecules: the immunoglobulin superfamily 28 11 The major histocompatibility complex 30 12 The T-cell receptor 32 13 Antibody diversification and synthesis 34 14 Antibody structure and function 36 (ii) The cellular basis 15 Lymphocytes 38 16 Primary lymphoid organs and lymphopoiesis 40 17 Secondary lymphoid organs and lymphocyte traffic 42 (iii) The adaptive immune response 18 Antigen processing and presentation 44 19 The antibody response 46 20 Antigen - antibody interaction and immune complexes 48 21 Cell-mediated immune responses 50 (iv) Regulation 22 Tolerance 52 23 Cell communication and cytokines 54 24 The cytokine network 56 25 Immunity, hormones and the brain 58 Potentially useful immunity 26 Antimicrobial immunity: a general scheme 60 27 Immunity to viruses 62 28 HIV and AIDS 64 29 Immunity to bacteria 66 30 Immunity to fungi and ectoparasites 68 31 Immunity to protozoa 70 32 Immunity to worms 72 Undesirable effects of immunity 33 Immunodeficiency 74 34 Harmful immunity: a general scheme 76 35 Allergy and anaphylaxis 78 36 Immune complexes, complement ...

List of contents

Preface 6
 
Acknowledgements 6
 
Note on the tenth edition 6
 
How to use this book 7
 
Further reading 7
 
List of abbreviations 8
 
Immunity
 
1 The scope of immunology 10
 
2 Innate and adaptive immune mechanisms 12
 
3 Recognition and receptors: the keys to immunity 14
 
4 Cells involved in immunity: the haemopoietic system 16
 
Innate immunity
 
5 Receptors of the innate immune system 18
 
6 Complement 20
 
7 Acute infl ammation 22
 
8 Phagocytic cells and the reticuloendothelial system 24
 
9 Phagocytosis 26
 
Adaptive immunity
 
(i) The molecular basis
 
10 Evolution of recognition molecules: the immunoglobulin superfamily 28
 
11 The major histocompatibility complex 30
 
12 The T-cell receptor 32
 
13 Antibody diversifi cation and synthesis 34
 
14 Antibody structure and function 36
 
(ii) The cellular basis
 
15 Lymphocytes 38
 
16 Primary lymphoid organs and lymphopoiesis 40
 
17 Secondary lymphoid organs and lymphocyte traffic 42
 
(iii) The adaptive immune response
 
18 Antigen processing and presentation 44
 
19 The antibody response 46
 
20 Antigen - antibody interaction and immune complexes 48
 
21 Cell-mediated immune responses 50
 
(iv) Regulation
 
22 Tolerance 52
 
23 Cell communication and cytokines 54
 
24 The cytokine network 56
 
25 Immunity, hormones and the brain 58
 
Potentially useful immunity
 
26 Antimicrobial immunity: a general scheme 60
 
27 Immunity to viruses 62
 
28 HIV and AIDS 64
 
29 Immunity to bacteria 66
 
30 Immunity to fungi and ectoparasites 68
 
31 Immunity to protozoa 70
 
32 Immunity to worms 72
 
Undesirable effects of immunity
 
33 Immunodeficiency 74
 
34 Harmful immunity: a general scheme 76
 
35 Allergy and anaphylaxis 78
 
36 Immune complexes, complement and disease 80
 
37 Chronic and cell-mediated infl ammation 82
 
38 Autoimmune disease 84
 
Altered immunity
 
39 Transplant rejection 86
 
40 Immunosuppression 88
 
41 Immunostimulation and vaccination 90
 
Immunity in health and disease
 
42 Cancer immunology 92
 
43 Immunity and clinical medicine 94
 
44 Investigating immunity 96
 
45 Immunology in the laboratory 98
 
46 Out of the past: evolution of immune mechanisms 100
 
47 Into the future: immunology in the age of genomics 102
 
Self-assessment
 
Self-assessment questions 105
 
Answers 107
 
Appendices
 
Appendix I Comparative sizes and molecular weights 109
 
Appendix II Landmarks in the history of immunology and some
 
unsolved problems 111
 
Appendix III CD classification 113
 
Index 115

Report

"This book provides a user-friendly overview of thebody's defence mechanisms. Ideal for a medical,biomedical or life science course, the text contains a basicoverview of both adaptive and innate immunity, appliedimmunological concepts, and how each body system can be affected byimmunity." ( European Journal of Immunology , 1December 2012)

Product details

• Authors: B M Chain, B. M. Chain, Chain B. M., J Playfair, J H Playfair, J H L Playfair, J. H. L. Playfair, J. H. L. (University College Playfair, J. H. L. Chain Playfair, Playfair J. H. L.
• Publisher: Wiley, John and Sons Ltd
• Languages: English
• Product format: Paperback / Softback
• Released: 02.11.2012
• EAN: 9780470673034
• ISBN: 978-0-470-67303-4
• No. of pages: 128
• Series: At a Glance; At a Glance
• Subjects: Natural sciences, medicine, IT, technology > Medicine > General; Medizin, Immunologie, Immunology, Medical Science, Basic Medical Sciences, Medizinische Grundlagenfächer