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Cytochrome c fulfills a central role in biological electron transport. This book draws together information from diverse disciplines in order to provide a common base for further research. The comprehensive treatment of this subject does not neglect to show the diversity of biological respirations and photosyntheses. But it also defines their unifying principles. This overview presents the evolutionary relatedness in bioenergetic systems. Such systems are discussed at the experimental level with emphasis on the interpretation of results and the methodological approaches used. No other text provides a broad survey of this central area of biology. Researchers on cytochrome c are presented with information on the impact and importance of other disciplines on their area of investigation. Advanced students gain a balanced account of biological electron transport and will be encouraged to seek new directions of research.
List of contents
1 Resolution, Characterisation and Classification of c-Type Cytochromes.- 1.1 Resolution.- 1.2 Characterisation.- 1.3 Classification.- References.- 2 The Role of Mitochondrial Cytochrome c in Electron Transport.- 2.1 Introduction.- 2.2 Reaction of Cytochrome c with the Inner Membrane Electron Transfer System.- 2.3 Reaction of Cytochrome c with Intermembrane Redox Systems.- 2.4 The Binding Surface of Cytochrome c.- 2.5 Structural Studies on the Electron Transfer Complexes of Cytochrome c.- 2.6 Ion Binding to Cytochrome c.- 2.7 Theoretical Aspects of Complex Formation by Cytochrome c.- 2.8 An Assessment of the Role of Cytochrome c in the Mitochondrion.- References.- 3 The Function of Bacterial and Photosynthetic Cytochromes c.- 3.1 Introduction.- 3.2 Donor Reactions to Cytochrome c - The bc1/bf Complex.- 3.3 Donor Reactions to Cytochrome c - Chemolithotrophy.- 3.4 Oxygen as a Terminal Electron Acceptor.- 3.5 Nitrate Respiration and Denitrification.- 3.6 The Oxidation of Cytochrome c by the Photosynthetic Reaction Centre.- 3.7 Sulfate Respiration and the Production of Sulfide.- References.- 4 The Biosynthesis of Cytochrome c.- 4.1 Gene Structure and the Control of Gene Expression.- 4.2 Posttranslational Processing and Modification.- References.
