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In the mid-1980s the European Journal of Biochemistry set out to publish review articles. The enterprise proved successful, resulting in high-level reviews written by well-known scientists appearing in the Journal. The reviews represent emerging and rapidly growing fields of research in fundamental as well as applied areas of biochemistry, such as medicine, biotechnology, agriculture and nutrition. Novel methodological and technological approaches which stimulate biochemical research are also included. The authors of the reviews are explicitly asked to be critical, selective, evaluative and interdisciplinary oriented. The reviews should encourage young scientists to think independently and creatively, and inform active investigators about the state of the art in a given field.
List of contents
Import and insertion of proteins into the mitochondrial outer membrane.- Does mitogen-activated-protein kinase have a role in insulin action? - The cases for and against.- T-cell antigen receptor-induced signal-transduction pathways - Activation and function of protein kinases C in T lymphocytes.- Protein kinase C in the transduction of signals toward and within the cell nucleus.- Signal recognition particle (SRP), a ubiquitous initiator of protein translocation.- Homologous nuclear-encoded mitochondrial and cytosolic isoproteins - A review of structure, biosynthesis and genes.- The MADS-box family of transcription factors.- The mechanism of dinitrogen reduction by molybdenum nitrogenases.- Platelet-activating factor produced by endothelial cells - A molecule with autocrine and paracrine properties.- The ability of actinic light to modify the bacteriorhodopsin photocycle - Heterogeneity and/or photocooperativity?.- The chaperonin containing t-complex polypeptide 1 (TCP-1) - Multisubunit machinery assisting in protein folding and assembly in the eukaryotic cytosol.- The structure of ribosomal RNA: a three-dimensional jigsaw puzzle.- Biosynthesis and biological activities of lantibiotics with unique post-translational modifications.- Ubiquitin and the enigma of intracellular protein degradation.- Regulation of globin gene expression in erythroid cells.- Mechanisms of nuclear signalling by vitamin D3 - Interplay with retinoid and thyroid hormone signaling.- The molecular biology of multidomain proteins - Selected examples.- Energised (entatic) states of groups and of secondary structures in proteins and metalloproteins.- Author index for EJB Reviews 1989-1995.
