Risk Assessment in Chemical Carcinogenesis

The essays in this book discuss the role that chemicalagents in the environment play in the development of cancer.Thus, it gives information toimprove our understanding ofcarcinogenesis and how to prevent it. The essays wereoriginally presented at an international symposium.

List of contents

Honorary lecture Risk Assessment and Management of Toxic Chemicals: The Needs and Guidelines for Developing Countries.- Molecular Basis of Risk Assessment.- Individual Genetic Constellations as Risk Factors in Chemical Carcinogenesis.- Mechanistic Analysis as a Tool for Carcinogen Risk Assessment.- Molecular Genetic Alterations such as Oncogene Activation as a Tool for the Evaluation of Risks in Chemical Carcinogenesis.- Initiation and Promotion - Useful Concepts for Risk Assessment?.- Human Exposure to Chemical Carcinogens.- Risk Assessment of Naturally Occurring Carcinogens.- Carcinogenic Drugs and their Relevance in Risk Assessment.- A Weight-of-Evidence Approach to Quantitative Cancer Risk Assessment: Information Analysis.- Biologically Based Pharmacokinetics and Cancer Risk Assessment.- Evaluation of Epidemiologic Study Designs for the Assessment of Risk in Chemical Carcinogenesis.- The Role of 'Negative' and 'Nonpositive' Studies in Occupational Epidemiology.- Weak Associations in Occupational Epidemiology and the Criteria for Deducing Causality.- Aspects of Clinical Oncology in the Assessment in Chemical Carcinogenesis.- Regulations in Risk Assessment.- Provisions on Carcinogenic Substances in the Federal Republic of Germany and the European Community.- Regulations on Chemical Carcinogenesis of the Environmental Protection Agency (EPA).- Regulation of Chemical Carcinogenesis in Japan.- Acknowledgements.- Invited Speakers and Chairmen.

Summary

The essays in this book discuss the role that chemical
agents in the environment play in the development of cancer.
Thus, it gives information toimprove our understanding of
carcinogenesis and how to prevent it. The essays were
originally presented at an international symposium.

Product details

• Assisted by: Thomas Klenner (Editor), Gotthard Schettler (Editor), Dietric Schmähl (Editor), Dietrich Schmähl (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 04.12.2012
• EAN: 9783540541493
• ISBN: 978-3-540-54149-3
• No. of pages: 172
• Dimensions: 165 mm x 242 mm x 8 mm
• Weight: 320 g
• Illustrations: IX, 172 p. 5 illus.
• Series: Sitzungsberichte der Heidelberger Akademie der Wissenschaften; Sitzungsberichte der Heidelberger Akademie der Wissenschaften / Sitzungsber.Heidelberg 91; Sitzungsberichte der Heidelberger Akademie der Wissenschaften; Sitzungsber.Heidelberg 91
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Clinical medicine; Physiologie, Anatomie, Onkologie, C, Medicine, Surgery, Anatomy, allgemeine Chirurgie, HUMAN ANATOMY, HUMAN PHYSIOLOGY, PHYSIOLOGY, INTERNAL MEDICINE, Oncology, general surgery