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Informationen zum Autor P. Vadgama is Director of the Interdisciplinary Research Centre in Biomedical Materials at Queen Mary! University of London. Klappentext This book presents our current level of understanding on the nature of a biomaterial surface! the adaptive response of the biomatrix to that surface! techniques used to modify biocompatibility! and state-of-the-art characterisation techniques to follow the interfacial events at that surface. Zusammenfassung This book presents our current level of understanding on the nature of a biomaterial surface, the adaptive response of the biomatrix to that surface, techniques used to modify biocompatibility, and state-of-the-art characterisation techniques to follow the interfacial events at that surface. Inhaltsverzeichnis Part 1 Forming methods: Fundamental properties of surfaces; Control of polymeric biomaterial surfaces; Organic thin film architectures: fabrication and properties; Membranes and permeable films; Stable use of biosensors at the sample interface; Micro- and nanoscale surface patterning techniques for localising biomolecules and cells: the essence of nanobiotechnology. Part 2 Measurement! monitoring and characterisation: Surface spectroscopies; Surface microscopies; Nanoidentation; Surface plasmon resonance; Ellipsometry for optical surface study applications; Neutron reflection; Microgravimetry. Part 3 Surface interactions and in-vitro studies: Interaction between biomaterials and cell tissues; Blood flow dynamics and surface interactions; Cell guidance through surface cues; Controlled cell deposition techniques; Biofouling in membrane separation systems. Part 4 Surface interactions and in-vivo studies: Bioactive 3D scaffolds in regenerative medicine: the role of interface interactions; Intravascular drug delivery systems and devices: interactions at biointerface; Surface degradation and microenvironmental outcomes; Microbial biofilms and clinical implants; Extracellular matrix molecules in vascular tissue engineering; Biomineralisation processes; On the topographical characterisation of biomaterial surfaces. Part 5 Appendices: Surface modification of polymers to enhance biocompatibility; Issues concerning the use of assays of cell adhesion to biomaterials; Protein adsorption to surfaces and interfaces. ...
