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All epidemiological data predict an endemic rise of prostate cancer in populations with a high proportion of elderly people, leading to a major health problem. The only way to stem this evolution is early detection in organised random- ised trials. Discussion of this controversial subject is followed by an exhaustive review of the endocrine mechanisms stimulating prostate growth and the promising avenues of future research and treatment. Radical prostatectomy and radiotherapy are presented and analysed. Once patients are past this stage of cure, a wide array of medical treatments are available. Endocrine treatment is the first choice, and the different regimes are reviewed as to their respective advantages and side effects. An entirely new approach to hormone refractory diseases completes this overview.
List of contents
Prostate Cancer 2000: Projections for the Future.- The Evolution of an Epidemic of Unknown Origin.- Remarks on Screening and Early Detection of Prostate Cancer.- Endocrine Aspects of Prostate Cancer.- The Diagnosis and Staging of Prostate Cancer.- Radical Prostatectomy.- Radiation Therapy of Prostate Cancer at Stanford University: An Experience of 36 Years.- Primary Endocrine Treatment of Advanced Prostate Cancer.- Hormone-Independent Prostate Cancer: Management of the Disease Continuum.
Summary
All epidemiological data predict an endemic rise of prostate cancer in populations with a high proportion of elderly people, leading to a major health problem. The only way to stem this evolution is early detection in organised random- ised trials. Discussion of this controversial subject is followed by an exhaustive review of the endocrine mechanisms stimulating prostate growth and the promising avenues of future research and treatment. Radical prostatectomy and radiotherapy are presented and analysed. Once patients are past this stage of cure, a wide array of medical treatments are available. Endocrine treatment is the first choice, and the different regimes are reviewed as to their respective advantages and side effects. An entirely new approach to hormone refractory diseases completes this overview.
