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Molecular biology has always been a discipline of rapid development. Despite this, we are presently experiencing a period of unprecedented proliferation of information in nucleic acid studies and molecular biology. These areas are intimately interwoven, so that each influences the other to their mutual benefit. The rapid growth in information leads to ever-increasing specialization, so that it becomes increasingly difficult for a scientist to keep abreast of developments in all the various aspects of the field, although an up-to-date knowledge of the field as a whole is highly desirable. With this background in mind we present the series Nucleic Acids and Molecular Biology. It comprises focused review articles by active researchers who report on the newest developments in their areas of particular interest.
List of contents
Laser Raman Spectroscopy of Nucleic Acids.- Non-Commensurate Polypurine/Polypyrimidine DNA Structures.- Sequence Specific Recognition of Double Helical DNA. A Synthetic Approach.- Metal Complexes Which Target DNA Sites: Coupling Recognition to Reactivity.- Mechanistic Studies of Bleomycin-Mediated DNA Cleavage Using Isotope Labeling.- Oligo-[?]-Deoxyribonucleotides Covalently Linked to Intercalating Agents. A New Family of Sequence-Specific Nucleic Acid Reagents.- The Efficiency of Oligonucleotide-Directed Mutagenesis.- Protein-Induced DNA Bending.- "Zinc Fingers": A Novel Motif for Nucleic Acid Binding.- NMR Studies of Repressor-Operator Interaction. The Lac Control Region.- DNA Repair by the Ada Protein of E. coli.- Homologous Pairing Promoted by Ustilago Rec 1 Protein.- Differential Interaction of the Receptors for Glucocorti- coids and Progestins with the Hormone Regulatory Element of MMTV.
