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Informationen zum Autor Horacio D. Espinosa, Northwestern University, USA Horacio D. Espinosa is the James and Nancy Farley Professor of Mechanical Engineering at Northwestern University, USA. He is a member of the European Academy of Arts and Sciences, and Fellow of AAM, ASME, and SEM. He served as Editor-in-chief of the Journal of Experimental Mechanics and Associate Editor of the Journal of Applied Mechanics. Currently, he is a co-editor of the Wiley Book Series in Micro and Nanotechnologies and serves in several journal editorial boards. His research interests include biomimetics, size scale electro-mechanical properties of nanomaterials, NEMS, in-situ microscopy testing of nanostructures, and the development of microdevices for tip-based nanofabrication and single cell studies. Gang Bao, Georgia Institute of Technology, USA Gang Bao is Professor of Bioengineering at the Georgia Institute of Technology, USA. His research interests include biomolecular engineering, bionanotechnology, molecular imaging and molecular biomechanics. Klappentext Research in nano and cell mechanics has received much attention from the scientific community as a result of society needs and government initiatives to accelerate developments in materials, manufacturing, electronics, medicine and healthcare, energy, and the environment. Engineers and scientists are currently engaging in increasingly complex scientific problems that require interdisciplinary approaches. In this regard, studies in this field draw from fundamentals in atomistic scale phenomena, biology, statistical and continuum mechanics, and multiscale modeling and experimentation. As a result, contributions in these areas are spread over a large number of specialized journals, which prompted the Editors to assemble this book.Nano and Cell Mechanics: Fundamentals and Frontiers brings together many of the new developments in the field for the first time, and covers fundamentals and frontiers in mechanics to accelerate developments in nano- and bio-technologies.Key features:* Provides an overview of recent advances in nano and cell mechanics.* Covers experimental, analytical, and computational tools used to investigate biological and nanoscale phenomena.* Covers fundamentals and frontiers in mechanics to accelerate developments in nano- and bio-technologies.* Presents multiscale-multiphysics modeling and experimentation techniques.* Examines applications in materials, manufacturing, electronics, medicine and healthcare.Nano and Cell Mechanics: Fundamentals and Frontiers is written by internationally recognized experts in theoretical and applied mechanics, applied physics, chemistry, and biology. It is an invaluable reference for graduate students of nano- and bio-technologies, researchers in academia and industry who are working in nano and cell mechanics, and practitioners who are interested in learning about the latest analysis tools. The book can also serve as a text for graduate courses in theoretical and applied mechanics, mechanical engineering, materials science, and applied physics. Zusammenfassung Research in nano and cell mechanics has received much attention from the scientific community as a result of society needs and government initiatives to accelerate developments in materials, manufacturing, electronics, medicine and healthcare, energy, and the environment. Inhaltsverzeichnis About the Editors xiii List of Contributors xv Foreword xix Series Preface xxi Preface xxiii Part One BIOLOGICAL PHENOMENA 1 Cell-Receptor Interactions 3 David Lepzelter and Muhammad Zaman 1.1 Introduction 3 1.2 Mechanics of Integrins 4 1.3 Two-Dimensional Adhesion 7 1.4 Two-Dimensional Motility 9 1.5 Three-Dimensional Adhesion 11 1.6 Three-Dimensional Motility 12 1.7 Apoptosis and Survival Signaling 13 1.8...
