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This book is a festschrift to mark the career of ogy, immunology and clinical aspects of each Dr David Tyrrell, eminent virologist and group. There are also more general chapters physician. Almost all of the contributors have overviewing the clinical manifestations, treat been colleagues or students at some time ment and pathophysiology of respiratory during his career. Unlike most festschrifts, virus infections. In addition, chapters in however, the essays have been integrated to which psychological aspects and the ethical produce a comprehensive book that covers use of human volunteers are discussed will be the entire field of non-bacterial infections of of interest to all those involved with respira the human respiratory tract. This is a measure tory infectious agents. of the breadth of interest of the research We hope also that this book serves as a undertaken by David, spanning a period of fitting tribute to a man who is a true poly over 40 years. math: a physician, researcher, teacher, We hope that this book will be of interest mentor, linguist and ambassador for science, to microbiologists, virologists and in particu among other things. To those of us who have lar, to physicians. All the major virus groups contributed to this book, he is even more: a are covered, as well as chlamydial and friend.
List of contents
1 Epidemiology of viral respiratory tract infections.- 2 The clinical spectrum of disease in adults.- 3 Clinical spectrum of disease in children.- 4 Diagnosis of viral respiratory tract infections.- 5 Pathophysiology of viral respiratory tract infections.- 6 Taxonomy of rhinoviruses - a history.- 7 Respiratory viral infections in the tropics.- 8 Rhinoviruses.- 9 Coronaviruses.- 10 Adenoviruses.- 11 Paramyxoviruses.- 12 Respiratory syncytial virus.- 13 Immunity to respiratory syncytial virus infections.- 14 Influenza viruses and vaccines.- 15 Influenza viruses: clinical spectrum and management.- 16 Respiratory hantaan virus.- 17 Mycoplasmas and their role in human respiratory tract disease.- 18 Chlamydia pneumoniae infections.- 19 Respiratory virus and mycoplasmal infections in the immunocompromised.- 20 The use of interferons in respiratory viral infections.- 21 Specific antiviral therapy of respiratory viruses.- 22 Antiviral activity of defective interfering influenza virus in vivo.- 23 Psychology of common colds and other infections.- 24 The ethical use of human volunteers in clinical research.
