Molecular Mechanisms of Aging

A high-level text on the molecular and genetic aspects of human ageing with reference to cognitive functions and age-related diseases.

List of contents

Cognitive Functions and Aging.- The Brain Disease of Aging - Epidemiology and Risk Factors of Senile Dementia (Alzheimer').- Cognition Related Functional, Praxis and Feeding Changes in CNS Aging and Alzheimer's Disease and their Developmental Analogies.- Genetics and Biology of Aging.- Genetical Aspects of Aging.- Aging and DNA Repair.- Gene Expression.- Transcription Factor Regulation in Brain: Focus on Activity and NMDA Dependent Regulation.- New Methods for Detecting DNA Sequence Variation in Relation to Aging.- Regulation of the Amyloid Gene of Alzheimer's Disease.- Membranes and Aging.- The Molecular Biology of Down Syndrome.- Aging of Cell Membrane Molecules: Band 3 and Senescent Cell Antigen in Neural Tissue.- Essential Macromolecular Structures for the Function of the Myelin Membrane of Central Nervous System.- Models.- Transgenic Mouse Model of Autosomal Dominant Disease: Familial Amyloidotic Polyneuropathy.- Somatostatin and Brain Aging.- Molecular Approaches to Age-Related Diseases.- Amyloidosis.- Amyloid ßA4 Protein Deposition in Alzheimer's Disease and Down's Syndrome.- Alzheimer's Disease and Animal Models.- Acknowledgements.- List of Participants.

Product details

• Assisted by: Konra Beyreuther (Editor), Konrad Beyreuther (Editor), Schettler (Editor), Schettler (Editor), Gotthard Schettler (Editor)
• Publisher: Springer, Berlin
• Languages: English
• Product format: Paperback / Softback
• Released: 16.11.2012
• EAN: 9783540527329
• ISBN: 978-3-540-52732-9
• No. of pages: 206
• Weight: 420 g
• Illustrations: VII, 206 p. 24 illus.
• Series: Sitzungsberichte der Heidelberger Akademie der Wissenschaften; Sitzungsberichte der Heidelberger Akademie der Wissenschaften / Sitzungsber.Heidelberg 90; Sitzungsberichte der Heidelberger Akademie der Wissenschaften; Sitzungsber.Heidelberg 90
• Subject: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine