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Informationen zum Autor Dhavendra Kumar, MD, FRCP, FACMG, is Professor, the University of Glamorgan, and Consultant in Clinical Genetics at the University Hospital of Wales, Institute of Medical Genetics, Cardiff University, Cardiff, United Kingdom. Klappentext Genomics and Health in the Developing World provides detailed and comprehensive coverage of population structures, human genomics, and genome variation - with particular emphasis on medical and health issues - in the emerging economies and countries of the developing world. With sections dedicated to fundamentals of genetics and genomics, epidemiology of human disease, biomarkers, comparative genomics, developments in translational genomic medicine, current and future health strategies related to genetic disease, and pertinent legislative and social factors, this volume highlights the importance of utilizing genetics/genomics knowledge to promote and achieve optimal health in the developing world. Grouped by geographic region, the chapters in this volume address: - Inherited disorders in the developing world, including a thorough look at genetic disorders in minority groups of every continent - The progress of diagnostic laboratory genetic testing, prenatal screening, and genetic counseling worldwide - Rising ethical and legal concerns of medical genetics in the developing world - Social, cultural, and religious issues related to genetic diseases across continents Both timely and vastly informative, this book is a unique and comprehensive resource for genetists, clinicians, and public health professionals interested in the social, ethical, economic, and legal matters associated with medical genetics in the developing world. Zusammenfassung This book is designed to be the first major text to discuss advances in medical genetics in the developing world. Inhaltsverzeichnis Contributors Part I: Genomics in Medicine and Health-General 1. Genes and Genomes in Health and Disease: An Introduction Dhavendra Kumar 2. The Human Variome Project and the Developing World Richard G.H. Cotton 3. Human Genomic Variation Initiatives in Emerging Economies and Developing Countries BÃ(c)atrice SÃ(c)guin, Billie-Jo Hardy, Peter A. Singer, and Abdallah S. Daar 4. The Genomic Map of Population Diversity in Asia Dhavendra Kumar 5. Ancestry, Disease and Variable Drug Response in the Genomic Era Charles Rotimi and Lynn Jorde 6. The Next Steps for Genomic Medicine: Challenges and Opportunities for the Developing World Billie-Jo Hardy, BÃ(c)atrice SÃ(c)guin, Federico Goodsaid, Gerardo JimÃ(c)nez-Sánchez, Peter A. Singer, and Abdallah S. Daar 7. Consumer Perspectives on Genomics and Healthcare Alastair Kent 8. Transcultural Perspectives on Genetics and Genomics Dhavendra Kumar 9. Medical Genetics and Genomics Research in the Muslim World Aida I. Al-Aqeel 10. The Progress of Genomics in the Developing World: Rising Social, Economic, and Ethical Concerns Minakshi Bhardwaj 11. Genetic Outcomes of Consanguineous Marriages Alan H. Bittles and Michael L. Black 12. Autosomal Recessive Conditions and Autozygosity Mapping Colin A. Johnson and Eamonn R. Maher 13. Genetic Contribution to Malaria Susceptibility and Resistance Susana G. Campino and Taane G. Clark 14. Glucose 6-Phosphate Dehydrogenase Deficiency: Genetics, Pharmacogenetics, and Malaria Selection Lucio Luzzatto 15. Infections, Genomics, and Global Public Health Tikki Pang 16. Microbial Genomics and Global Health Rino Rappuoli 17. Pharmacogenetics and Pharmacogenomics in the Developing World Warren E. Hochfeld, Sahle M. Asfaha, Marco Alessandrini, Tyren M. Dodgen, Renier Myburgh, Arinda Eloff, and Michael S. Pepper 18. Nutrigenomic Research in World Populations Jim Kaput 19. Transgenic Foods and Nutritional Health in D...
