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Informationen zum Autor Jerzy Leszczynski is Professor of Chemistry and a President's Distinguished Fellow. Director of Interdisciplinary Nanotoxicity Center. Author and co-author of almost 700 peer-reviewed papers (H index 47) and 50 book chapters. Klappentext Nanotechnology is one of the most promising and rapidly-expanding areas of science and the development of new materials on the nanoscale can benefit many disciplines, including chemistry, physics, and medicine. However, novel nanomaterials can possess a negative impact on human health and the environment and their development should be accompanied by a comprehensive risk assessment. Until now, information on the methods available for this purpose has been fragmented. This book presents a comprehensive review of the latest achievements in risk-assessing novel nanomaterials, drawing on expertise from across the globe. Both empirical methodologies and computational techniques are presented, and the editors advise that both groups of techniques are required for a complete risk assessment. Anyone developing new nanomaterials (in academia or industry) will find this book an essential reference. Toxicologists and environmental scientists will also benefit from learning the latest tools used for detecting nanomaterials in the environment. Zusammenfassung This book is the first to provide a comprehensive review of recent progress and challenges in the risk assessment of nanomaterials by empirical and computational techniques. Inhaltsverzeichnis Nanomaterials: benefits and risks; Experimental characterizing structural properties of nanoparticles related to their toxicity; Structure-property mapping methods; Modelling properties of nanoparticles based on quantum-mechanical methods; Ontology; Empirical determination of nanoparticles' behavior in environmental media; Computational mass-ballance modeling of environmental transport and fate of engineered nanoparticles; Pharmacokinetics and biological fate of nanoparticles; Pharmacokinetic-based modeling; Modeling kinetics of nanoparticle cellular interaction and transport; Toxicity and Ecotoxicity testing of engineered nanoparticles - experimental point of view; In vitro toxicity of nanomaterials; In vivo testing; Computational modeling of interactions between nanoparticles and other species; Comprehensive Environmental Assessment as a Tool for Nanomaterial Risk Assessment; Predicting oxidative stress; Nano-QSAR...
