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Informationen zum Autor Michael Jaffe is the Director of the Medical Device Concept Laboratory and Research Professor in Biomedical Engineering and Chemistry at the New Jersey Institute of Technology (NJIT)! USA. Willis B. Hammond is a Research Professor in the Department of Biomedical Engineering at NJIT. Peter Tolias is Director of the Bio-innovation Program and a Research Professor in the Schaefer School of Engineering and Science at the Stevens Institute of Technology! USA. Treena Arinzeh is Professor of Biomedical Engineering at NJIT. Klappentext Biomaterials and medical devices must be rigorously tested in the laboratory before they can be implanted. Testing requires the right analytical techniques. Characterization of biomaterials reviews the latest methods for analyzing the structure, properties and behaviour of biomaterials. Beginning with an introduction to microscopy techniques for analyzing the phase nature and morphology of biomaterials, Characterization of biomaterials goes on to discuss scattering techniques for structural analysis, quantitative assays for measuring cell adhesion, motility and differentiation, and the evaluation of cell infiltration and tissue formation using bioreactors. Further topics considered include studying molecular-scale protein-surface interactions in biomaterials, analysis of the cellular genome and abnormalities, and the use of microarrays to measure cellular changes induced by biomaterials. Finally, the book concludes by outlining standards and methods for assessing the safety and biocompatibility of biomaterials. With its distinguished editors and international team of expert contributors, Characterization of biomaterials is an authoritative reference tool for all those involved in the development, production and application of biomaterials. "Brief, yet very well-written and useful overview, suitable for specialists as well as researchers new to the field."-Dr. Aleksandr Ovsianikov (Institute of Materials Science and Technology, Vienna University of Technology), www.biomt.net Zusammenfassung Characterization of biomaterials reviews the latest methods for defining properties and characterizing materials. Inhaltsverzeichnis Contributor contact details Woodhead Publishing Series in Textiles Chapter 1: Microscopy techniques for analyzing the phase nature and morphology of biomaterials Abstract: 1 Introduction: basic imaging concepts 1.2 Image perception and interpretation 1.3 Light microscopy 1.4 Laser scanning confocal microscopy (LSCM) 1.5 Scanning electron microscopy (SEM) 1.6 Atomic force microscopy (AFM) Chapter 2: Scattering techniques for structural analysis of biomaterials Abstract: 2.1 Introduction 2.2 Light scattering 2.3 Wide-angle X-ray diffraction 2.4 Measuring orientation using X-ray diffraction 2.5 Small-angle scattering techniques 2.6 Small-angle X-ray scattering (SAXS) 2.7 Small-angle neutron scattering (SANS) 2.8 Acknowledgment Chapter 3: Quantitative assays for measuring cell adhesion and motility in biomaterials Abstract: 3.1 Introduction 3.2 Cell attachment assays 3.3 Cell adhesion strength 3.4 Collective motility of cell populations 3.5 Individual cell motility 3.6 Conclusion and future trends Chapter 4: Assays for determining cell differentiation in biomaterials Abstract: 4.1 Introduction 4.2 Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) assays 4.3 Protein and chemical assays 4.4 Imaging assays 4.5 Future trends Chapter 5: Bioreactors for evaluating cell infiltration and tissue formation in biomaterials Abstract: 5.1 Introduction 5.2 Bioreactor designs 5.3 Evaluation of cell infiltration and ce...
