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Nanotechnology is at the forefront of advances in medicine. Nanomedicine: Technologies and applications provides an important review of this exciting technology and its growing range of applications. After an introduction to nanomedicine, part one discusses key materials and their properties, including nanocrystalline metals and alloys, nanoporous gold and hydroxyapatite coatings. Part two goes on to review nanomedicine for therapeutics and imaging, before nanomedicine for soft tissue engineering is discussed in part three, including organ regeneration, skin grafts, nanotubes and self-assembled nanomaterials. Finally, nanomedicine for bone and cartilage tissue engineering is the focus of part four, with electrically active biocomposites as smart scaffolds investigated, as is cartilage and bone tissue engineering, regeneration and replacement. With its distinguished editor and international team of expert contributors, Nanomedicine: Technologies and applications is an indispensable guide for all those involved in the research, development and application of this exciting technology, whilst providing a comprehensive introduction for students and academics interested in this field. Provides an important review of nanomedicine technology and its growing range of applications Discusses key nanomedicine materials and their properties, including nanocrystalline metals and alloys, nanoporous gold and hydroxyapatite coatings Reviews nanomedicine for therapeutics and imaging and nanomedicine for soft tissue engineering
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Woodhead Publishing Series in Biomaterials
Dedication
Part I: Materials, properties and considerations
Chapter 1: Introduction to nanomedicine
Abstract:
1.1 Introduction: basic concepts of nanomedicine
1.2 Public perception of nanomedicine
1.3 Scientific principles and applications of nanomedicine
1.4 Future trends in nanomedicine
Chapter 2: Trends in nanomedicine
Abstract:
2.1 Introduction
2.2 The rise of nanomedicine
2.3 Diagnostics and medical records
2.4 Treatment
2.5 Future trends
Chapter 3: Biomedical nanocrystalline metals and alloys: structure, properties and applications
Abstract:
3.1 Introduction
3.2 Synthesis and structure of nanocrystalline metals and alloys
3.3 Properties of nanocrystalline metals and alloys
3.4 Biocompatibility of nanocrystalline metals and alloys
3.5 Applications of nanocrystalline metals and alloys
3.6 Future trends
3.7 Sources of further information and advice
Chapter 4: Nanoporous gold for biomedical applications: structure, properties and applications
Abstract:
4.1 Introduction
4.2 Medical applications
4.3 Biosensor applications
4.4 Alloy formation
4.5 Dealloying of gold-silver alloy
4.6 Mechanical properties of nanoporous gold
4.7 Electronic properties of nanoporous gold
4.8 Conclusions
Chapter 5: Hydroxyapatite (HA) coatings for biomaterials
Abstract:
5.1 Introduction
5.2 Hydroxyapatite (HA) coatings
5.3 HA coatings by plasma spraying
5.4 Properties of plasma-sprayed coatings
5.5 Biomimetic HA coatings
5.6 HA coatings by sol-gel deposition
5.7 Miscellaneous deposition techniques for HA coatings
5.8 Conclusions
5.9 Future trends
5.10 Acknowledgement
Part II: Nanomedicine for therapeutics and imaging
Chapter 6: Calcium phosphate-coated magnetic nanoparticles for treating bone diseases
Abstract:
6.1 Introduction
6.2 Iron oxide magnetic nanoparticle synthesis
6.3 Surface modification of iron oxide magnetic nanoparticles
6.4 Characterization of iron oxide magnetic nanoparticles
6.5 Biological applications of magnetic nanoparticles
6.6 Conclusions
6.7 Future trends
Chapter 7: Orthopedic carbon nanotube biosensors for controlled drug delivery
Abstract:
7.1 Introduction
7.2 Carbon nanotubes for electrochemical biosensing
7.3 Carbon nanotube-based in situ orthopedic implant sensors
7.4 Electrically controlled drug-delivery systems for infection and inflammation
7.5 Critical issues in developing in situ orthopedic implantable sensors and devices
7.6 Conclusions
Chapter 8: Nanostructured selenium anti-cancer coatings for orthopedic applications
Abstract:
8.1 Introduction
8.2 Selenium as an anti-cancer implant material
8.3 Nanostructured selenium coatings: a novel approach of using selenium to create anti-cancer biomaterials
8.4 In vitro biological assays for uncoated and selenium-coated metallic substrates
8.5 The effectiveness of titanium and stainless steel substrates
8.6 Coarse-grained Monte Carlo computer simulation of fibronectin adsorption on nanometer rough surfaces
8.7 Conclusions
Chapter 9: Nanoparticulate targeted drug delivery using peptides and proteins
Abstract:
9.1 Introduction
9.2 Peptides and proteins for targeted drug delivery
9.3 Drug-peptide conjugates
9.4 Peptide-functionalized drug delivery systems
9.5 Peptide-targeted drug delivery across the intestine
9.6 Peptide-targeted drug delivery across the blood-brain barrier (BBB)
9.7 Peptide-targeted drug delivery for cancer applicatio
