Mechanosensitive Ion Channels

This book explores the latest data dealing with mechanosensitive channels research results. It was compiled by a group of internationally recognized scientists leading in the field of mechanosensitive ion channels or mechanically gated channels and signaling cascades research. Key problems of cell mechanobiology are also discussed. As a whole, the volume dwells on the major issues of mechanical stress influencing the ion channels and intracellular signaling pathways.

List of contents

Mechanosensitive Channels.- Experimental Methods of Studying Mechanosensitive Channels and Possible Errors in Data Interpretation.- Role of Lipid Bilayer Mechanics in Mechanosensation.- Mechanosensitive Channels Gated by Membrane Tension.- Computational Studies of the Bacterial Mechanosensitive Channels.- Mechanosensory Transduction in the Nematode Caenorhabditis elegans.- Mechanosensitive Ion Channels in Odontoblasts.- Potassium Ion Channels in Articular Chondrocytes.- Osmotransduction Through Volume-Sensitive Cl- Channels.- Mechanosensitive Channel TRPV4.- Mechanosensitive Signalling Cascades.- Mechanosensitive Purinergic Calcium Signalling in Articular Chondrocytes.- Signal Transduction Pathways Involved in Mechanotransduction in Osteoblastic and Mesenchymal Stem Cells.- Caveolae.- Multimodal Activation and Regulation of Neuronal Mechanosensitive Cation Channels.- Regulation of Intracellular Signal Transduction Pathways by Mechanosensitive Ion Channels.- Cell Mechanobiology.- The Effects of Mechanical Stimulation on Vertebrate Hearts.- Mechanobiology of Fibroblasts.

Summary

This book explores the latest data dealing with mechanosensitive channels research results. It was compiled by a group of internationally recognized scientists leading in the field of mechanosensitive ion channels or mechanically gated channels and signaling cascades research. Key problems of cell mechanobiology are also discussed. As a whole, the volume dwells on the major issues of mechanical stress influencing the ion channels and intracellular signaling pathways.

Product details

• Authors: J. Hescheler, M. J. Lab
• Assisted by: Andre Kamkin (Editor), Irin Kiseleva (Editor), Irina Kiseleva (Editor), I Lozinsky (Editor), I. Lozinsky (Editor), J. Hescheler (Foreword), M.J. Lab (Foreword)
• Publisher: Springer Netherlands
• Languages: English
• Product format: Paperback / Softback
• Released: 29.01.2013
• EAN: 9789048176380
• ISBN: 978-90-481-7638-0
• No. of pages: 382
• Dimensions: 155 mm x 21 mm x 235 mm
• Weight: 608 g
• Illustrations: XXII, 382 p.
• Series: Mechanosensitivity in Cells and Tissues; Mechanosensitivity in Cells and Tissues
• Subjects: Natural sciences, medicine, IT, technology > Biology > General, dictionaries; B, Zoology & animal sciences, Biomedical and Life Sciences, Medical physics, Biophysics, Animal Physiology, Applied mathematics, Biological physics, Biological and Medical Physics, Biophysics, Cell Biology, Biomathematics, Mathematical and Computational Biology, Physiological, Cellular and Medical Topics