Handbook of Radiopharmaceuticals - Radiochemistry and Applications

Klappentext The Handbook of Radiopharmaceuticals is an up-to-date! authoritative reference that introduces key issues relating to the production and application of radiopharmaceuticals. The book covers a wide range of radiochemistry and clinical applications including the production of various radionuclides! positron emission tomography (PET) and drug development. Discussions on the uses of radiopharmaceuticals in the diagnosis and therapy of cancer and other diseases are also included.Features include:* 28 Chapters contributed by world-renowned experts in the field* All aspects of radiopharmaceutical production and applications are discussedWritten by internationally recognised authors! the Handbook of Radiopharmaceuticals is an invaluable resource for advanced graduates and researchers within radiochemistry! analytical and organic chemistry! drug delivery and pharmacokinetics! biochemistry and pharmacology. This book will also be of interest to clinicians! radiologists and radiographers involved in nuclear medicine and radiology. Radiopharmaceuticals are being increasingly utilized as surrogate markers in drug evaluations. This book will be useful to scientists involved in drug development. Zusammenfassung This comprehensive reference provides an up-to-date introduction to the key issues relating to the production and application of radiopharmaceuticals. The book covers a wide range of radiochemistry and clinical applications including the production of various radionuclides! positron emission tomography (PET) and drug development. Inhaltsverzeichnis Foreword.Production of Radionuclides in Accelerators (Schlyer).Accelerators available for Isotope Production (Ruth).Reactor Production of Radionuclides (Mausner and Mirzadeh).Chemistry of Nitrogen-13 and Oxygen-15 (Clark and Aigbirhio).Aspects of the Synthesis of 11C-Labelled Compounds (Antoni et al).Chemistry of Fluorine-18 Radiopharmaceuticals (Snyder and Kilbourn).Production and Application of Synthetic Precursors Labeled with Carbon-11 and Fluorine-18 (Ferrieri).Automation for the Synthesis and Application of PET Radiopharmaceuticals (Alexoff).Design and Synthesis of 2-Deoxy-2-[18F]Fluoro-D-Glucose (18FDG) (Fowler and Ido).Technetium Radiopharmaceuticals (Mahmood and Jones).Chemistry of Gallium and Indium Radiopharmaceuticals (Weiner and Thakur).Chemistry of Copper Radionuclides and Radiopharmaceutical Products (Anderson et al).Chemistry applied to Iodine Radionuclides (Finn).Radiobromine for Imaging and Therapy (Rowland et al).Development of Radiolabeled Probes to monitor Gene Therapy (Shiue and Eck).Mechanisms of Target Specific Uptake using Examples of Muscarinic Receptor Binding Radiotracers (Eckelman).Strategies for quantifying PET Imaging Data from Tracer Studies of Brain Receptors and Enzymes (Logan).Radiopharmaceuticals for studying the Heart (Hwang and Bergmann).PET Imaging Studies in Drug Abuse Research (Fowler et al).Research and Clinical Application of Neuroreceptor Imaging (Wagner and Szabo).Dynamic Neurotransmitter Interactions measured with PET (Schiffer and Dewey).Tumor Imaging (Hustinx and Alavi).Radiolabeled Peptides for Tumor Imaging (Knight).Radiolabeled Anitbodies for Tumor Imaging and Therapy (Zalutsky and Lewis).Receptor Imaging of Tumors (Non-peptide) (Katzenellenbogen).Pulmonary Function Imaging with PET Radiopharmaceuticals (Elsinga and Vaalburg).Considerations in the Selection of Radionuclides for Cancer Therapy (Kassis and Adelstein).Radiopharmaceuticals for the Study of Liver and Renal Function (Vera et al). ...

List of contents

Foreword.Production of Radionuclides in Accelerators (Schlyer).Accelerators available for Isotope Production (Ruth).Reactor Production of Radionuclides (Mausner and Mirzadeh).Chemistry of Nitrogen-13 and Oxygen-15 (Clark and Aigbirhio).Aspects of the Synthesis of 11C-Labelled Compounds (Antoni et al).Chemistry of Fluorine-18 Radiopharmaceuticals (Snyder and Kilbourn).Production and Application of Synthetic Precursors Labeled with Carbon-11 and Fluorine-18 (Ferrieri).Automation for the Synthesis and Application of PET Radiopharmaceuticals (Alexoff).Design and Synthesis of 2-Deoxy-2-[18F]Fluoro-D-Glucose (18FDG) (Fowler and Ido).Technetium Radiopharmaceuticals (Mahmood and Jones).Chemistry of Gallium and Indium Radiopharmaceuticals (Weiner and Thakur).Chemistry of Copper Radionuclides and Radiopharmaceutical Products (Anderson et al).Chemistry applied to Iodine Radionuclides (Finn).Radiobromine for Imaging and Therapy (Rowland et al).Development of Radiolabeled Probes to monitor Gene Therapy (Shiue and Eck).Mechanisms of Target Specific Uptake using Examples of Muscarinic Receptor Binding Radiotracers (Eckelman).Strategies for quantifying PET Imaging Data from Tracer Studies of Brain Receptors and Enzymes (Logan).Radiopharmaceuticals for studying the Heart (Hwang and Bergmann).PET Imaging Studies in Drug Abuse Research (Fowler et al).Research and Clinical Application of Neuroreceptor Imaging (Wagner and Szabo).Dynamic Neurotransmitter Interactions measured with PET (Schiffer and Dewey).Tumor Imaging (Hustinx and Alavi).Radiolabeled Peptides for Tumor Imaging (Knight).Radiolabeled Anitbodies for Tumor Imaging and Therapy (Zalutsky and Lewis).Receptor Imaging of Tumors (Non-peptide) (Katzenellenbogen).Pulmonary Function Imaging with PET Radiopharmaceuticals (Elsinga and Vaalburg).Considerations in the Selection of Radionuclides for Cancer Therapy (Kassis and Adelstein).Radiopharmaceuticals for the Study of Liver and Renal Function (Vera et al).

Report

"...a must for all colleagues who are involved in radiopharmaceuticals, either at the bench or at the bedside." ( Eur Jnl Nuc Med Mol Imaging , August 2003)
"...a unique text that lives up to its goals...a very competent reference for anyone wishing to immerse themselves into the world of radiopharmaceuticals." ( The Annals of Phamacotherapy , Vol. 37, November 2003)

"...every aspect of importance in this field is discussed...an excellent overview..." (Eur Jnl Med Mol Imaging, 2003)

Product details

• Authors: Michael J. Welch, Carol S. Redvanly, Michael Welch, Michael J. Welch, Michael J. Redvanly Welch, WELCH MICHAEL J REDVANLY CAROL
• Assisted by: Carol S. Redvanly (Editor), Michael J. Welch (Editor)
• Publisher: Wiley, John and Sons Ltd
• Languages: English
• Product format: Hardback
• Released: 27.11.2002
• EAN: 9780471495604
• ISBN: 978-0-471-49560-4
• No. of pages: 862
• Subject: Natural sciences, medicine, IT, technology > Biology > Miscellaneous