Fr. 188.00

Infection, Immune Homeostasis and Immune Privilege

English · Hardback

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Description

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Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated "immune-privileged sites" by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms.

This volume highlights the mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection.

List of contents

Introduction.- The Eye as Immune Privileged Site.- Immune Privilege of the Testis - Meaning, Mechanisms and Manifestations.- The Role of Intrauterine Immune Privilege in Perinatal Infectious Diseases.- The Liver as an Immune Privileged Site.- Immune Homeostasis of the Lung: The Role of Regulatory NKT Cells in Asthma.- Immune Homeostasis of the Gut.

Summary

Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated “immune-privileged sites” by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms. This volume highlights the mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection.

Product details

Assisted by Joa Stein-Streilein (Editor), Joan Stein-Streilein (Editor)
Publisher Springer, Basel
 
Languages English
Product format Hardback
Released 22.03.2012
 
EAN 9783034804448
ISBN 978-3-0-3480444-8
No. of pages 156
Dimensions 169 mm x 15 mm x 245 mm
Weight 368 g
Illustrations XII, 156 p.
Series Birkhäuser Advances in Infectious Diseases
Birkhäuser Advances in Infectious Diseases
Subject Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine

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