Advanced Research on Animal Cell Technology

List of contents

I. Cell-Cell Communication and Cell Extracellular Matrix Interactions.- Extracellular Matrix Cell Differentiation.- Structure and Function of the Heparan Sulfate Proteoglycans.- Role Played by Gap Junctions in Cell-Cell Communication.- Fibronectin-Mediated Cellular (Inter)actions.- II. "Normal" Versus "Abnormal" Cells.- Use of Cell Lines in Biotechnology.- Why Not Use Primary Cells.- III. Large Scale Cultivation of Animal Cells.- Technology of Mass Cultivation: An Overview.- Cell Culture in Hollow Fibre Bioreactors.- Perfusion Culture.- Good Manufacturing Practice in the Production of Biologicals by Cell Cultures.- Biosensors.- IV. Analysis of the Cell's Behaviour.- Effects of Retinoids on Growth Differentiation.- Phosphoinositide Metabolism and Control of Cell Proliferation.- Somatic Cell Genetic Analysis of Growth Control.- Promoter Organization of Eukaryotic Protein-Coding Genes.- V. Modification of the Cell Genome.- Tailoring of an Anti-Human Placental Alkaline Phosphatase Immunoglobulin Using Genetic Engineering.- Vaccinia Virus as an Expression Vector.- Expression and Integration of Exogenous DNA Seguences Transfected into Mammalian Cells.- Cooperation of Oncogenes in Malignant Transformation.- VI. Applications of Animal Cell Cultures.- Molecular Dissection of the Cell Cycle.- Use of Microbeads for Cell Transplantation.- Influence of Epigenetic Factors on Epidermal Differentiation and Morphogenesis.- The Characterization of Fibroblast Growth Factor and Its Biological Effect In Vitro and In Vivo.- Culture of Hybridomas - A Survey.- Applications of Chromatography in Downstream Processing.- General discussion.

Summary

Proceedings of the NATO Advanced Research Workshop, Brussels, Belgium, September 21-24, 1987

Product details

• Authors: Ron Miller, NATO Advanced Research Workshop on Advan, North Atlantic Treaty Organization
• Assisted by: A.O.A. Miller (Editor), Alain O a Miller (Editor), Alain O. A. Miller (Editor), Alain O.A. Miller (Editor)
• Publisher: Springer Netherlands
• Languages: English
• Product format: Hardback
• Released: 05.12.2012
• EAN: 9780792300311
• ISBN: 978-0-7923-0031-1
• No. of pages: 432
• Weight: 910 g
• Illustrations: 432 p.
• Series: NATO Science Series E: (Closed; Theory and Decision Library; NATO Science Series E; NATO Science Series: E: Applied Sciences; Theory and Decision Library; Nato Science Series E:
• Subject: Natural sciences, medicine, IT, technology > Medicine > Clinical medicine