Bound Carbohydrates in Nature

Summary of Professor Waren's pivotal research on the special properties of bound carbohydrates in nature.

List of contents

1. Introduction, history, microheterogeneity of bound carbohydrates; function of bound carbohydrates; inducible changes in bound carbohydrates; programmed changes in bound carbohydrates; a possible role for bound carbohydrates; 2. Sialic acids; distribution of sialic acids in nature; the metabolism of hexamines and sialic acids; metabolic control of hexosamines and sialic acids; asparagine N-glycosylation; processing of lysomal enzymes; biosynthesis of O-linked oligosaccarides; modification of sialic acids; sialidases; genetic metabolic disorders involving sialic acids, glycosidases, bound carbohydrates in malignancy; 3. Multidrug resistance, properties of P-glycoprotein; lysomes and multidrug resistance; kinetics of influx and efflux of drugs, modulation of multidrug resistance; the role of lipids in the accumulation of drugs by MDR cells; P-170 and membrane lipids; Overview.

Summary

This 1994 book is based on a series of six lectures given at the Accademia dei Lincei. The contents focus on the special properties of bound carbohydrates in nature. It will prove an instructive and entertaining first hand account for researchers and graduate students.

Product details

• Authors: Leonard Warren, Warren Leonard
• Publisher: Cambridge Academic
• Languages: English
• Product format: Hardback
• Released: 17.02.1994
• EAN: 9780521442312
• ISBN: 978-0-521-44231-2
• Dimensions: 140 mm x 216 mm x 11 mm
• Weight: 310 g
• Illustrations: 30 b/w illus. 7 tables, Zeichnungen, nicht spezifiziert, Tabellen, nicht spezifiziert
• Series: Lezioni Lincee; Lezioni Lincee
• Subjects: Natural sciences, medicine, IT, technology > Medicine > Clinical medicine; ORGANIC CHEMISTRY, SCIENCE / Life Sciences / Biology, SCIENCE / Chemistry / Organic, biochemistry, CARBOHYDRATES, Chemical biology