Gene Therapy in the Treatment of Cancer - Progress and Prospects

Reviews progress and considers future developments in the fast-evolving field of gene therapy in oncology.

List of contents

Contributors; Preface; 1. Introduction: gene therapy approaches to cancer Brian E. Huber; 2. Principles of transformation-directed cancer therapy Ian Magrath and Kishor Bhatia; 3. Vectors for cancer gene therapy Prem Seth; 4. Genetically engineering drug sensitivity and drug resistance for the treatment of cancer Brian E. Huber; 5. Oncogene inactivation and replacement strategies for cancer Jack A. Roth; 6. Genetically modified tumor cells as tumor vaccines John C. Krauss, Suyu Shu and Alfred E. Chang; 7. Genetically modified lymphocytes and hematopoietic stem cells as therapeutic vehicles Patrick J. Geraghty and James J. Mulé; 8. Pharmacologic effects of oligonucleotides and some clinical applications Leonard M. Neckers and Kanak Iyer; 9. Current status of gene marking and gene therapy in oncology clinical trials Cynthia A. Richards; 10. Safety testing for gene therapy products J. Patrick Condreay; Index.

Summary

Drawing on laboratory studies and clinical trials, including the work of the contributors themselves, this timely volume in the series Cancer: Clinical Science in Practice reviews progress in the fast-evolving field of gene therapy in oncology and looks forward to future developments.

Product details

• Assisted by: Brian E. Huber (Editor), Ian Magrath (Editor), Ian T. Magrath (Editor), Karol Sikora (Editor)
• Publisher: Cambridge University Press
• Languages: English
• Product format: Hardback
• Released: 23.04.2014
• EAN: 9780521444361
• ISBN: 978-0-521-44436-1
• No. of pages: 230
• Dimensions: 157 mm x 235 mm x 17 mm
• Weight: 490 g
• Series: Cancer: Clinical Science in Pr
• Subject: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine