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Klappentext The vast majority of medically important pathogens infect their host across a body surface such as the skin, or across a mucosal tissue such as the respiratory tract or intestines, as these sites are the ones exposed to the external environment. By focusing on immunity at mucosal and body surfaces this book presents a fresh, new approach to the teaching of immunology.After an introduction to the basic structure of the immune system, the book looks at two important families of signalling molecules: cytokines and chemokines, before covering the workings of the mucosal immune system. It continues by examining immunity against the four major groups of pathogens - viruses, bacteria, fungi and parasites, and concludes by looking at disorders of the immune system, mucosal tumour immunology and the process of vaccination.* A fresh, new approach to the subject focusing on mucosal and body surfaces.* Describes the mucosal immune systems of the gastrointestinal, respiratory and urogenital tracts, as well as the skin.* Details the important roles of cytokines and chemokines in an immune response.* Separate chapters devoted to immunity against viruses, bacteria, fungi and parasites.* Includes chapter summaries, boxes with topics of special interest and an extensive glossary.* Clearly written and well- illustrated in full colour throughout.Students across a range of disciplines, including biology, biochemistry, biomedicine, medicine and veterinary sciences, will find this book invaluable, both as an introduction to basic immunology and as a guide to mucosal immune defence mechanisms. Zusammenfassung Immunity: Mucosal Immunology in Health and Disease provides a realistic approach to the teaching of immunology! dealing with immunity at specific sites in the body a novel approach not adopted in current books. This book is the first immunology textbook to focus on the mucosa! the largest immune organ in the body. Inhaltsverzeichnis Preface, xvList of Standard Cells and Symbols, xvii1 Basic Concepts in Immunology, 12 The Innate Immune System, 203 The Adaptive Immune System, 414 Cytokines, 685 Chemokines, 936 Basic Concepts in Mucosal Immunology, 1117 Immunology of the Gastrointestinal Tract, 1338 Immunology of the Airways, 1569 Immunology of the Urogenital Tract and Conjunctiva, 17710 Immunology of the Skin, 19611 Immunity to Viruses, 21712 Immunity to Bacteria, 23813 Immunity to Fungi, 25814 Immunity to Parasites, 27815 Disorders of the Immune System, 30216 Mucosal Tumour Immunology, 32217 Vaccination, 342Glossary of Terms, 363Index, 374...
