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Informationen zum Autor Laurie K. McCauley , DDS, PhD is the William K. and Mary Anne Najjar Professor and Chair of the Department of Periodontics and Oral Medicine, and Professor in the Department of Pathology at the University of Michigan in Ann Arbor, Michigan. Martha J. Somerman , DDS, PhD, formerly Dean and Professor, University of Washington School of Dentistry, is currently the Director of the National Institute of Dental and Craniofacial Research, and Chief, Laboratory for Oral Connective Tissue Biology, National Institute of Arthritis and Musculoskeletal and Skin Diseases at the National Institutes of Health in Bethesda, Maryland. Klappentext Mineralized Tissues in Oral and Craniofacial Science is a major comprehensive update on knowledge in the field of mineralized tissues in the oral and craniofacial region. Drs. McCauley and Somerman assembled an international team of researchers and clinicians, offering a global perspective on the current knowledge in this field. Basic and clinical correlates reinforce the significance of research to clinical diagnoses and therapies, written in a manner that lends easily to their use for case study teaching venues.Section 1 features the many aspects of bone in the craniofacial region, including embryology, cell biology, and stem cell biology. Section 2 focuses on teeth-tooth development, dentin, enamel, cementum, and tooth regeneration. Section 3 discusses the interaction between bones and teeth, including those associated with inflammatory processes, periodontal ligaments, biomechanics, and other impact factors-such as nutrition, metabolic bone diseases and therapeutic modalities.The novel approach of linking the basic principles of the cell and molecular biology of hard tissues to clinical correlates will appeal to readers at all levels of their research careers, both students and faculty; faculty interested in a comprehensive text for reference; and clinicians interested in the biologic aspects of bones and teeth. Zusammenfassung Mineralized Tissues in Oral and Craniofacial Science is a major comprehensive update on knowledge in the field of mineralized tissues in the oral and craniofacial region. Drs. McCauley and Somerman assembled an international team of researchers and clinicians, offering a global perspective on the current knowledge in this field. Inhaltsverzeichnis Contributors vii Preface xv Acknowledgments xvii Foreword xix Section 1 Bones of the oral-dental and craniofacial complex 1 1 Embryology of craniofacial bones 3 Antonio Nanci and Pierre Moffatt 2 Clinical correlate: cleft lip and palate 13 Emily R. Gallagher and Joel Berg 3 Cell and molecular biology of the osteoclast and bone resorption 17 Martin Biosse-Duplan, William C. Horne, and Roland Baron 4 Clinical correlate: osteopetrosis 29 Paul C. Edwards and Nasser Said-Al-Naief 5 Clinical correlate: CLCN7-associated autosomal recessive osteopetrosis 35 Piranit Nik Kantaputra 6 Osteoblasts of craniofacial bone 43 Renny T. Franceschi, Chunxi Ge, and Christopher G. Wilson 7 Clinical correlate: cleidocranial dysplasia 59 Shu Takeda, Nobuhiko Haga, and Keiji Moriyama 8 Cell biology of craniofacial bone: osteocytes 63 Lynda F. Bonewald 9 Clinical correlate: Van Buchem disease 71 H.-J. Prins, A.L.J.J. Bronckers, and J. Klein-Nulend 10 Stem cell biology in the craniofacial apparatus 79 Carolina Parada, Kentaro Akiyama, Yang Chai, and Songtao Shi 11 Clinical correlate: stem cell therapy for craniofacial bone regeneration 93 Giorgio Pagni, William V. Giannobile, and Darnell Kaigler 12 Extracellular matrix and mineralization of craniofacial bone 99 Marc D. McKee, Monzur Murshed, and Mari T. Kaarti...
