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Informationen zum Autor Daniel A. Beard is a Professor in the Biotechnology and Bioengineering Center and the Department of Physiology at the Medical College of Wisconsin. Research in his laboratory is focused on systems engineering approaches to understanding the operation of physiological systems in health and disease. A recent major effort in his group has been on theoretical and experimental characterization of the thermodynamics, kinetics and electrophysiology of cardiac mitochondria. Additional research interests include non-equilibrium thermodynamics in biochemical networks, mass transport and microvascular exchange in physiological systems, and drug metabolism and physiologically-based pharmacokinetics. Klappentext A hands-on guide to devising, designing and analyzing simulations of biophysical processes for applications in biological and biomedical sciences. Zusammenfassung A hands-on guide to devising! designing and analyzing simulations of biophysical processes for applications in biological and biomedical sciences. Practical examples are given throughout! representing real-world case studies of key application areas! and all data and complete codes for simulation and data analysis are provided online. Inhaltsverzeichnis 1. Introduction to simulation of biological systems; 2. Transport and reaction of solutes in biological systems; 3. Physiologically-based pharmacokinetic modeling; 4. Cardiovascular systems simulation; 5. Chemical reaction systems: thermodynamics; 6. Chemical reaction systems: kinetics; 7. Chemical reaction systems: large-scale systems simulation; 8. Cellular electrophysiology; 9. Appendices: mathematical and computational techniques.
