NON NEOPLASTIC HEMATOPATHOLOGY AND

Informationen zum Autor Hernani Cualing MD , is Associate Professor in the Department of Pathology and Cell Biology and Director of the Hematopathology Fellowship Training Program at the University of South Florida College of Medicine in Tampa, Florida. He is also an active hematopathologist at the Moffitt Cancer Center and Research Institute there. In addition to his research into such topics as mantle cell and T cell lymphomas, Dr. Cualing has long been fascinated with the analysis, diagnosis, and treatment of non-neoplastic and infectious blood, marrow, and lymph diseases. Parul Bhargava, MD, is Medical Director in the Hematology Laboratory at Beth Israel Deaconess Medical Center-Needham Campus in Boston, and a staff and faculty physician in the Pathology department there. Her primary research interests are in studying hematopoietic neoplasms and newer markers in Hodgkin Lymphoma, but she also has a strong, separate clinical interest in studying the effects of immunodeficiency and infections, particularly HIV, on the hematopoietic system. Ramon L. Sandin, MD, MS, FCAP, ABP-MM, is a Clinical Pathologist and Medical Director of Clinical Microbiology and Virology in the Department of Hematopathology, Laboratory Medicine, and in the Blood and Marrow Transplant Program at the Moffitt Cancer Center in Tampa, Florida 33612-9497. His special areas of expertise and research interests are in clinical microbiology and virology, and laboratory diagnosis of infectious diseases. This includes 'wet' laboratory work-ups and tissue section diagnosis as well as molecular diagnostic techniques. Klappentext Most books on hematopathology are neoplastic in scope and offer little non-neoplastic content. In Non-Neoplastic Hematopathology and Infections, the authors fully describe the hematologic manifestations in tissue and blood of infectious agents, including many rare and exotic diseases found in both Western and Eastern hemispheres, in order to assist pathologists and medical laboratory professionals all over the world in better diagnosing and treating such infections.Thoroughly illustrated with photographs, tables and text, this book features a wide range of non-neoplastic hematologic disorders, as well as reactive patterns of non-infectious and infectious agents. Comprehensive and state-of-the-art diagnostic materials are described, as are the epidemiology, pathobiology, clinical and pathologic manifestations in blood and lymphatic organs--as well as the approaches to treatment.In addition, Non-Neoplastic Hematopathology and Infections:* Contains detailed information on the pathology and patterns of blood, lymph node, and a number of bone marrow and splenic infections and infectious agent manifestations* Thoroughly updates the classic pathology of reactive lymphadenopathies and extends this pattern-based approach to tropical and emergent infections* Promotes the multidisciplinary integration of hematopathologists and microbiologists in the analysis and diagnostic work-up of tissue and blood* Complements current major treatises on such tropical diseases as Manson's, Ashworth's, and Doerr's and updates the classic tomes of William St. Clair Symmers and current texts on neoplastic hematopathologyNon-Neoplastic Hematopathology and Infections is an important book for any medical professional interested in non-neoplastic hematology, infections and tissue hematopathology, infectious diseases and tropical medicine, and tropical hematopathology. Zusammenfassung Many infectious agents disseminate in blood and the lymphatic system, and many of these infections are also tropical diseases that affect a large segment of the world s population, including travelers, immigrants, and refugees. Inhaltsverzeichnis Contributors, xix Foreword, xxiii Preface, xxv Acknowledgments, xxvii Introduction, xxix PART I Non-neoplastic Hematology 1 ...

List of contents

Contributors, xix
 
Foreword, xxiii
 
Preface, xxv
 
Acknowledgments, xxvii
 
Introduction, xxix
 
PART I Non-neoplastic Hematology 1
 
CHAPTER ONE Non-neoplastic Disorders of White Blood Cells 3
Rebecca A. Levy, Vandita P. Johari, and Liron Pantanowitz
 
Overview of WBC Production and Function, 3
 
Quantitative Disorders of WBCS, 6
 
Qualitative Disorders of WBCS, 21
 
References, 26
 
CHAPTER TWO Non-neoplastic Disorders of Platelets 31
Lija Joseph
 
Platelet Production Structure and Function, 31
 
Quantitative Disorders of Platelets, 33
 
Qualitative Disorders of Platelets, 39
 
References, 43
 
CHAPTER THREE Approach to Disorders of Red Blood Cells 45
Jason C. Ford
 
Introduction, 45
 
The Anemias, 45
 
The Approach to Anemia, 50
 
The Polycythemias, 63
 
References, 63
 
CHAPTER FOUR Microcytic, Normocytic, and Macrocytic Anemias 65
Reza Setoodeh and Loveleen C. Kang
 
Microcytic Anemias, 65
 
Normocytic Anemias, 74
 
Macrocytic Anemias, 81
 
References, 86
 
CHAPTER FIVE Disorders of Hemoglobin 89
Parul Bhargava
 
Overview, 89
 
Quantitative Disorders of Hemoglobin, 89
 
Qualitative Disorders of Hemoglobin, 97
 
Mixed-Quantitative Qualitative Disorders of Hemoglobin, 104
 
Double Heterozygous States, 105
 
Approach to Diagnosis of Hemoglobin Disorders, 106
 
References, 111
 
PART II Infectious Aspects of Hematology 113
 
CHAPTER SIX Apicomplexal Parasites of Peripheral Blood, Bone Marrow, and Spleen: The Genera Plasmodium, Babesia, and Toxoplasma 115
Lynne S. Garcia
 
Plasmodium, 115
 
Babesia, 125
 
Toxoplasma, 128
 
References, 134
 
CHAPTER SEVEN Blood and Tissue Flagellates of the Class Kinetoplastidea: The Genera Leishmania and Trypanosoma 139
Raul E. Villanueva and Stephen D. Allen
 
Leishmaniasis, 139
 
Chagas' Disease, 145
 
African Trypanosomiasis, 150
 
References, 155
 
CHAPTER EIGHT Proteobacteria and Rickettsial Agents: Human Granulocytic Anaplasmosis and Human Monocytic Ehrlichiosis 159
Sheldon Campbell and Tal Oren
 
Microbiology and Epidemiology of HGA and HME, 159
 
Clinical Syndromes, 160
 
Differential Diagnosis, 160
 
Diagnostic Approach, 161
 
Prevention and Treatment, 163
 
References, 163
 
CHAPTER NINE Clinically Significant Fungal Yeasts 165
Ramon L. Sandin
 
Introduction, 165
 
Histoplasma capsulatum var. capsulatum (H. capsulatum), 166
 
Blastomyces dermatitidis, 170
 
Coccidioides immitis, 174
 
Cryptococcus neoformans, 178
 
Candida albicans and other Candida Species, 183
 
Malassezia furfur, 188
 
References, 193
 
CHAPTER TEN Hematologic Aspects of Tropical Infections 195
Deniz Peker
 
Anemia in Tropical Infections, 195
 
Vascular Purpuras, 202
 
References, 203
 
PART III Non-neoplastic Lymph Node Pathology and Infections 205
 
CHAPTER ELEVEN Classification of Reactive Lymphadenopathy 207
Hernani D. Cualing
 
Introduction, 207
 
References, 229
 
CHAPTER TWELVE Lymph Node Biology, Markers and Disease 231
Hernani D. Cualing
 
Peripheral Lymphoid Tissue, 231
 
Pathophysiology, 231
 
Cortex, 232
 
Paracortex, 240
 
Sinus Histiocytes, 242
 
Epithelioid Histiocytes
 
and Granulomas, 243
 
Nodal Framework, 243
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Report

"An ambitious book . . . comprehensive in coverage of the wide range of non-neoplastic hematopathology. It has a particular emphasis on tropical and non-tropical infectious diseases including parasitic diseases. It should be especially useful for hematologists, hematopathologists, general pathologists, and infectious disease specialists, but should also be useful for internists, primary care physicians, and those in training. It particularly emphasizes morphologic aspects of infections which may have hematologic manifestations or present diagnostic problems." - James Warren Smith, MD, Nordschow Professor Emeritus of Laboratory Medicine, Former Chair, Department of Pathology and Laboratory Medicine, Indiana University School of Medicine; Past President, Binford-Dammin Society of Infectious Disease Pathologists

Product details

• Authors: Paru Bhargava, Parul Bhargava, Bhargava Parul, Cualing, H Cualing, Hernan Cualing, Hernani Cualing, Hernani Bhargava Cualing, Cualing Hernani, CUALING HERNANI BHARGAVA PARUL S, Ramon L Sandin, Ramon L. Sandin, Sandin Ramon L.
• Publisher: Wiley, John and Sons Ltd
• Languages: English
• Product format: Hardback
• Released: 27.04.2012
• EAN: 9780470646007
• ISBN: 978-0-470-64600-7
• No. of pages: 608
• Subjects: Natural sciences, medicine, IT, technology > Medicine > General; Hämatologie, Pathologie, Medizin, Pathology, Hematology, Medical Science, Laboratory Hematology, Hämatologisches Labor