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Informationen zum Autor Fuyu Tamanoi is a biochemist who has served on the UCLA School of Medicine and UCLA College faculty since he joined the Department of Microbiology, Immunology & Molecular Genetics in 1993. He became a full professor in 1997. Klappentext This volume of The Enzymes features high-caliber thematic articles on the topic of glycosylphosphatidylinositol (GPI) anchoring of proteins. Zusammenfassung Features thematic articles on the topic of glycosylphosphatidylinositol (GPI) anchoring of proteins. This title informs on developments in the field. Inhaltsverzeichnis CAAX Processing and yeast a-factor biogenesis Jemima Barrowman and Susan Michaelis Geranylgeranyltransferase-1 inhibitors Norbert Berndt, Andrew D. Hamilton and Saïd M. Sebti Small molecule inhibitors of GGTase-I from the heterocycle library derived from phosphine catalysis Lai N. Chan, Masaru Watanabe, Ohyun Kwon and Fuyuhiko Tamanoi Inhibition of Rab prenylation E. Anouk Stigter, Gemma Triola, Roger S. Goody, Herbert Waldmann The Ras Converting Enzyme (Rce1p): Orthologs, Enzymology and Inhibitors Timothy M. Dore and Walter K. Schmidt Cysmethynil, A Specific Small Molecule Inhibitor of Isoprenylcysteine Carboxylmethyl Transferase (Icmt) Mei Wang The Isoprenoid Biosynthetic Pathway and Statins Sarah A. Holstein Inhibition of Farnesyl and Geranylgeranyl Diphosphate Synthases Sarah A. Holstein and Raymond J. Hohl
List of contents
CAAX Processing and yeast a-factor biogenesis
Jemima Barrowman and Susan Michaelis
Geranylgeranyltransferase-1 inhibitors
Norbert Berndt, Andrew D. Hamilton and Saïd M. Sebti
Small molecule inhibitors of GGTase-I from the heterocycle library derived from phosphine catalysis
Lai N. Chan, Masaru Watanabe, Ohyun Kwon and Fuyuhiko Tamanoi
Inhibition of Rab prenylation
E. Anouk Stigter, Gemma Triola, Roger S. Goody, Herbert Waldmann
The Ras Converting Enzyme (Rce1p): Orthologs, Enzymology and Inhibitors
Timothy M. Dore and Walter K. Schmidt
Cysmethynil, A Specific Small Molecule Inhibitor of Isoprenylcysteine Carboxylmethyl Transferase (Icmt)
Mei Wang
The Isoprenoid Biosynthetic Pathway and Statins
Sarah A. Holstein
Inhibition of Farnesyl and Geranylgeranyl Diphosphate Synthases
Sarah A. Holstein and Raymond J. Hohl
