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Informationen zum Autor George R. Uhl, NIDA, NIH, Baltimore, MD. Klappentext This volume features expert, refereed reviews of timely topics in each of the areas relevant to addiction science and clinical practice to aid researchers and practitioners interested in addictions. Authors from the United States, EU, Asia and elsewhere provide an international perspective on the problems and practices.Specifically, this volume:- focuses on topics that are relevant to specific substances but also provides important lessons for addiction to all substances- provides reviews that are aimed to be useful to specialists in the field and as useful to students as the first criterion allows.NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member. Zusammenfassung This volume features expert, refereed reviews of timely topics ineach of the areas relevant to addiction science and clinicalpractice to aid researchers and practitioners interested inaddictions. Authors from the United States, EU, Asia and elsewhereprovide an international perspective on the problems and practices. Inhaltsverzeichnis Introduction to Addiction reviews 2 / by George R. Uhl 1 Preface to Addiction reviews 2 / by George F. Koob 3 Part I. Medications for addiction and relevant neurotransmitter systems. Current perspectives on selective dopamine D3 receptor antagonists as pharmacotherapeutics for addictions and related disorders / by Christian A. Heidbreder and Amy H. Newman 4 Cocaine-induced neuroadaptations in glutamate transmission : potential therapeutic targets for craving and addiction / by Heath D. Schmidt and R. Christopher Pierce 35 Agonist-like pharmacotherapy for stimulant dependence : preclinical, human laboratory, and clinical studies / by David V. Herin, Craig R. Rush and John Grabowski 76 Part II. Drug and HIV toxicities Amphetamine toxicities : classical and emerging mechanisms / by Bryan K. Yamamoto, Anna Moszczynska and Gary A. Gudelsky 101 Human immunodeficiency virus-associated neurocognitive disorder : pathophysiology in relation to drug addiction / by Avindra Nath 122 Part III. Physiology. Synaptic plasticity in the mesolimbic system : therapeutic implications for substance abuse / by Billy T. Chen, F. Woodward Hopf and Antonello Bonci 129 Electrophysiological correlates of abused drugs : relation to natural rewards / by Sam A. Deadwyler 140 Part IV. Imaging. Neurochemistry of drug action : insights from proton magnetic resonance spectroscopic imaging and their relevance to addiction / by Stephanie C. Licata and Perry F. Renshaw 148 Part V. Development. Cocaine addiction in mothers : potential effects on maternal care and infant development / by Lane Strathearn and Linda C. Mayes 172 Part VI. Genetics. Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment / by Vadim Yuferov [and others] 184 Addictions and their familiality in Iceland / by Thorarinn Tyrfingsson [and others] 208 Transgenic mice in the study of drug addiction and the effects of psychostimulant drugs / by Ichiro Sora [and others] 218 Part VII. Behavioral mechanisms. Conditioned taste aversion learning : implications for animal models of drug abuse / by Catherine M. Davis and Anthony L. Riley 247 Part V...