Fr. 819.00

LOCK AND KEY PRINCIPLE - STATE OF THE ART 100 YEARS ON

English · Hardback

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Informationen zum Autor Jean-Paul Behr is the editor of The Lock-and-Key Principle: The State of the Art--100 Years On , published by Wiley. Klappentext Perspectives in Supramolecular Chemistry Editorial Board Founding Editor J.-M. Lehn, Université Louis Pasteur, Strasbourg, France Editors J.-P. Behr, Université Louis Pasteur, Strasbourg, France G. R. Desiraju, University of Hyderabad, Hyderabad, India A. D. Hamilton, University of Pittsburgh, Pittsburgh, USA T. Kunitake, Kyushu University, Fukuoka, Japan D.N. Reinhoudt, University of Twente, AE Enschede, The Netherlands J.-P. Sauvage, Université Louis Pasteur, Strasbourg, France Perspectives in Supramolecular Chemistry -- Volume 1 The Lock and Key Principle The State of the Art--100 Years On Edited by Jean-Paul Behr Université Louis Pasteur, Strasbourg, France Contributors Ian M. Bell, The Scripps Research Institute, La Jolla, USA S. J. Benkovic, Pennsylvania State University, Pennsylvania, USA F. Cramer, Max-Plank Institut für Experimentelle Medizin, Göttingen, Germany D. Hilvert, The Scripps Research Institute, La Jolla, USA E. A. Horovitz, The Weizmann Institute of Science, Rehovot, Israel E. Katchalski-Katzir, The Weizmann Institute of Science, Rehovot, Israel H. Kuhn, formerly Max-Planck-Institut für biophysikalische Chemie, Göttingen M. Lahav, The Weizmann Institute of Science, Rehovot, Israel D. Lancet, The Weizmann Institute of Science, Rehovot, Israel J.-M. Lehn, Université Louis Pasteur, Strasbourg, France L. Leiserowitz The Weizmann Institute of Science, Rehovot, Israel D. B. Smithrud, Pennsylvania State University, Pennsylvania, USA V. V. Vlassov, Institute of Bioorganic Chemistry, Novosibirsk, Russia Forthcoming titles in Perspectives in Supramolecular Chemistry Volume 2: Supramolecular Chemistry in the Solid State Edited by Gautam Desiraju, University of Hyderabad, India This volume will concentrate on the crystalline structures of supramolecules. Contributions will include Crystals as Supramolecules, Molecular Shape Considerations in Crystals Engineering, The Intermolecular Implication of Protein Function and Molecular Engineering of Crystals by Electrostatic Templating. Volume 3: Supramolecular Control of Structure and Reactivity Edited by Andrew Hamilton, Massachusetts Institute of Technology, Cambridge, USA This volume will deal with the catalytic properties of supramolecules, particularly in biological systems. Topics covered include Design of Self-Replicating Molecules, Synthetic Control of Oligonucleotide Structure, Micellar Catalysis and A Survey of Recent Developments in Supramolecular Catalysis. Zusammenfassung Celebrates the centenary of Emil Fischer's "lock-and-key" principle! which laid the foundation of molecular recognition. All aspects of the principle are discussed by researchers in the field of supramolecular chemistry! and suggestions are offered for areas of future research. Inhaltsverzeichnis Contributors vii Preface ix 1 Emil Fischer's Lock-and-Key Hypothesis after 100 Years-Towards a Supracellular Chemistry 1 Friedrich Cramer 2 Molecular Recognition in Biology: Models for Analysis of Protein-Ligand Interactions 25 Doron Lancet, Amnon Horovitz and Ephraim Katchalski-Katzir 3 New Biocatalysts via Chemical Modification 73 Ian M. Bell and Donald Hilvert 4 Oligonucleotides: Superspecific Ligands for Targeting Nucleic Acids and Proteins and Development of Molecular Devices 89 V. V. Vlassov 5 Macrocycles and Antibodies as Catalysts 149 D. B. Smithrud and S. J. Benkovic 6 Lock-and-Key Processes at Crystalline Interfaces: Relevance to the Spontaneous Generation of Chirality 173 Isabelle Weissbuch, Ronit Popovitz-Biro, Leslie Leiscrowitz and Meir Lahav 7 A Model of the Origin of Life and ...

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