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GENERALIZED SEIZURES FROM CLINICAL PHENO

English, French · Hardback

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A "Generalized seizure" corresponds to
an ictal manifestation whose initial
semeiology indicates, or is consistent
with, more than minimal involvement of
both cerebral hemispheres. A network is a
functionally and anatomically connected set of cortical
and subcortical brain regions in which activity in any
one part affects activity in all others. A system is a
group of independent but interrelated elements
(networks) comprising a unified whole. A considerable
amount of evidence supports the existence of specific
cortical and subcortical networks in the genesis,
expression and control of generalized seizures. Animal
and human data suggested that the so-called
generalized seizures involve selective networks while
sparing others. A greater understanding of those
systems and networks, thoroughly debated in this
book, will ultimately lead to improved targeted
therapies for so-called generalized epilepsies.

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