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Informationen zum Autor Alvin C. Powers, M.D. is the Joe C. Davis Chair in Biomedical Science Professor, Medicine, and Molecular Physiology and Biophysics. Director, Vanderbilt Diabetes Center. Director, Division of Diabetes and Endocrinology. Dr. Powers is a physician-scientist whose research on type 1 and type 2 diabetes focuses on pancreatic islet biology, development, and function. His research is or has been supported by the NIH, the VA Research Service, the JDRF, and the American Diabetes Association (ADA). Dr. Powers is also the Director of the Vanderbilt Medical Student Research Training Program in Diabetes, Endocrinology, and Metabolism and the Coordinator for the NIDDK Medical Student Research Program in Diabetes. Klappentext The Year in Diabetes and Obesity will fulfill a critical need in by publishing timely, thought-provoking reviews on the molecular, basic, and clinical aspects of diabetes and obesity. Reviews in the inaugural issue will include: Early life nutrition and Metabolic Programming; Neuroendocrine Responses to Hypoglycemia; Cardiovascular Outcomes in Type 2 Diabetes: The Impact of Preventative Therapies; Gastrointestinal Hormones and beta-cell Mass Regulation; CNS leptin and Insulin Action in the Control of Energy Homeostasis; The Genetics of Type 2 Diabetes: What have we learned from GWAS?; Management of Hyperglycemia in Hospitalized Patients; Circadian control of metabolism; Metabolic surgery for type 2 diabetes; and Adipokines.NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.1111/(ISSN)1749-6632.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member. Zusammenfassung The Year in Diabetes and Obesity will fulfill a critical need in by publishing timely, thought-provoking reviews on the molecular, basic, and clinical aspects of diabetes and obesity. Inhaltsverzeichnis Pathogenesis of type 1 diabetes: lessons from natural studies ofhigh-risk individuals 1 Natalie Nokoff and Marian Rewers The role of reactive oxygen species and proinflammatorycytokines in type 1 diabetes pathogenesis 16 Lindsey E. Padgett, Katarzyna, A. Broniowska, Polly A. Hansen,John A. Corbett and Hubert M. Tse Cardiovascular disease and glycemic control in type 2 diabetes:now that the dust is settling from large clinical trials 36 Francesco Giorgino, Anna Leonardini and Luigi Laviola Type 2 diabetes in South Asians: similarities and differenceswith white Caucasian and other populations 51 Unjali P. Guyral, R. Pradeepa, Mary Beth Weber, K.M. VenkatNarayan and V. Mohan Type 2 diabetes in East Asians: similarities and differenceswith population in Europe and the United States 64 Ronald C.W. Ma and Juliana C.N. Chan Islet ß cell mass in diabetes and how it relates tofunction, birth, and death 92 Gordon C. Weir and Susan Bonner-Weir Nanoalcoholic fatty liver disease: an emerging threat to obeseand diabetic individuals 106 Howard C. Masuoka and Naga Chalasani What is metabolic syndrome, and why are children getting it23 Ram Weiss, Andrew A. Bremer and Robert H. Lustig Physical activity in obesity and metabolic syndrome 141 Barbara Strasser Human adipose dynamics and metabolic health 160 Bin Feng, Tracy Zhang and Haiyan Xu The genetics of human obesity 178 Qianghua Xia and Struan F.A. Grant Managing obesity in primary care practice: a narrative review191 Raymond Carvajal, Thomas A. Wadden, Adam G. Tsai, KatherinePeck a...