Fr. 189.00

TT Viruses - The Still Elusive Human Pathogens

English · Paperback / Softback

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Description

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Eleven years ago the circular DNA of a novel single-stranded virus has been cloned and partially characterized by Nishizawa and Okamoto and their colleagues. According to the initials of the patient from whom the isolate originated, the virus was named TT virus. This name has been subsequently changed by the International Committee on Taxonomy of Viruses (ICTV) into Torque teno virus, permitting the further use of the abbreviation TTV. Although initially suspected to play a role in non A -E hepatitis, subsequent studies failed to support this notion.
Within a remarkably short period of time it became clear that TT viruses are widely spread globally, infect a large proportion of all human populations studied thus far and represent an extremely heterogeneous group of viruses, now labelled as Anelloviruses. TT virus-like infections have also been noted in various animal species. The classification of this virus group turns out to be difficult, their DNA contains between 2200 and 3800 nucleotides, related so-called TT-mini-viruses and a substantial proportion of intragenomic recombinants further complicate attempts to combine these viruses into a unifying phylogenetic concept.

List of contents

History of Discoveries and Pathogenicity of TT Viruses.- Classification of TTV and Related Viruses (Anelloviruses).- TT Viruses in Animals.- Replication of and Protein Synthesis by TT Viruses.- Immunobiology of the Torque Teno Viruses and Other Anelloviruses.- Intragenomic Rearrangement in TT Viruses: A Possible Role in the Pathogenesis of Disease.- TT Viruses: Oncogenic or Tumor-Suppressive Properties?.- Relationship of Torque Teno Virus to Chicken Anemia Virus.- Apoptosis-Inducing Proteins in Chicken Anemia Virus and TT Virus.- Chicken Anemia Virus.- Geminiviruses.

Summary

Eleven years ago the circular DNA of a novel single-stranded virus has been cloned and partially characterized by Nishizawa and Okamoto and their colleagues. According to the initials of the patient from whom the isolate originated, the virus was named TT virus. This name has been subsequently changed by the International Committee on Taxonomy of Viruses (ICTV) into Torque teno virus, permitting the further use of the abbreviation TTV. Although initially suspected to play a role in non A –E hepatitis, subsequent studies failed to support this notion.
Within a remarkably short period of time it became clear that TT viruses are widely spread globally, infect a large proportion of all human populations studied thus far and represent an extremely heterogeneous group of viruses, now labelled as Anelloviruses. TT virus-like infections have also been noted in various animal species. The classification of this virus group turns out to be difficult, their DNA contains between 2200 and 3800 nucleotides, related so-called TT-mini-viruses and a substantial proportion of intragenomic recombinants further complicate attempts to combine these viruses into a unifying phylogenetic concept.

Product details

Assisted by Ethel-Michel de Villiers (Editor), Ethel-Michele de Villiers (Editor), Ethel-Michele de Villiers (Editor), Zur Hausen (Editor), Zur Hausen (Editor), Harald Zur Hausen (Editor)
Publisher Springer, Berlin
 
Languages English
Product format Paperback / Softback
Released 09.02.2011
 
EAN 9783642089985
ISBN 978-3-642-08998-5
No. of pages 233
Dimensions 156 mm x 235 mm x 13 mm
Weight 374 g
Illustrations X, 233 p.
Series Current Topics in Microbiology and Immunology
Current Topics in Microbiology and Immunology
Subjects Natural sciences, medicine, IT, technology > Biology > Microbiology

Anatomie, Onkologie, C, Anatomy, HUMAN ANATOMY, Oncology, proteins, Biomedical and Life Sciences, Cancer Research, Virology, Cancer Biology

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