Contemporary Challenges in Autoimmunity, Volume 1173

This volume features key presentations from the 6th International Congress of Autoimmunity. The International Congress of Autoimmunity has become established as one of the major meetings in the field of immunology, with presentations covering every aspect of basic research in the hopes of clarifying pathogenesis of autoimmune disease as well as providing information on the latest innovations in biological and other modes of treatment. The goal of this volume is to present cutting edge research that focuses in particular on newer diagnostic tools and newer therapies for human autoimmune disease.NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

List of contents

Part I. Challenging Issues in the Diagnosis and Evaluation ofAutoimmune Disease.
1. Do We Need Autoimmune Disease Units in Hospitals?

2. Autoantibody Standardization in the Netherlands : The Past,the Present, and the Future.

3. Evaluation of a New ELISA Assay for Detection of BP230Autoantibodies in Bullous Pemphigoid.

4. Accuracy of the First Fully Automated Method forAnti-cardiolipin and Anti-2 Glycoprotein I Antibody Detection forthe Diagnosis of Antiphospholipid Syndrome.

5. New Developments in Serodiagnosis of Childhood Celiac Disease: Assay of Antibodies against Deamidated Gliadin.

6. Celiac G+ Antibody Assay for the Detection of Autoantibodiesin Celiac Disease.

7. High-sensitivity Detection of Autoantibodies AgainstProteinase-3 by a Novel Third-generation Enzyme-linkedImmunosorbent Assay.

8. Anti-C1q Autoantibodies in Lupus Nephritis.

9. Seronegative Autoimmune Diseases.

10. Correlation Between Clinical Activity and SerologicalMarkers in a Wide Cohort of Patients with Systemic LupusErythematosus : An Eight-year Prospective Study.

11. Circulating Cardiac Troponin-I Autoantibodies in HumanPlasma and Serum.

12. Choroid Plexus Connexin 43 Expression and Gap JunctionFlexibility Are Associated with Clinical Features of Acute EAE.

13. Autoantigens Identified by Screening a Human Heart cDNALibrary with Acute Rheumatic Fever Sera.

14. Optimization of High-throughput Autoantibody Profiling forthe Discovery of Novel Antigenic Targets in RheumatoidArthritis.

15. White Blood Cell Count Abnormalities and Infections inOne-year Follow-up of 124 Patients with SLE.

16. Clinical Significance of Complement Deficiencies.

17. An Italian Multicenter Study for Application of a DiagnosticAlgorithm in Autoantibody Testing.

18. Antibodies to Neurofilaments : Clinical and ImmunogeneticAssociations in Down Syndrome.

19. Possible Involvement of Chemokine-induced PlateletActivation in Thrombophilic Diathesis of Antiphospholipid Syndrome: An Attractive Target for the NF-B-specific InhibitorDHMEQ.

20. Prevalence of Anticardiolipin Antibodies in Patient Cohortswith Distinct Clinical Manifestations of the AntiphospholipidSyndrome.

21. Characterization of Antibodies Directed against theImmunoglobulin Light Chain Variable Chain Region (VK) ofHepatitis C Virus-Related Type-II Mixed Cryoglobulinemia and B-CellProliferations.

22. DNA-Bound Lactoferrin Is the Major Target for AntineutrophilPerinuclear Cytoplasmic Antibodies in Ulcerative Colitis.

23. Autoantibody Detection Using Indirect Immunofluorescence onHEp-2 Cells.

24. Autoantibody Screen in Inflammatory Myopathies HighPrevalence of Antibodies to Gliadin.

25. High Sensitive Detection of Double-Stranded DNAAutoantibodies by a Modified Crithidia luciliae ImmunofluorescenceTest.

26. The Incidence of Celiac Disease Antibodies in PlasmaSpecimens with Low Hemoglobin Levels.

27. Development of Recombinant Human IgA for AnticardiolipinAntibodies Assay Standardization.

28. Pneumatosis Intestinalis Presenting in Autoimmune Diseases :A Report of Three Patients.

29. Autoimmune Bullous Dermatoses: A Review.

30. Autoimmune Thyroid Disease and Autoimmune RheumaticDisorders : A Two-sided Analysis.

31. Cognitive Functioning in Behçet s Disease.

32. Alexithymia in Systemic Lupus Erythematosus Patients.

33. Anti-C1q Antibodies in Juvenile-Onset Systemic LupusErythematosus.

34. A New Year in Autoimmunity.

35. Relevance of Anti-C1q Autoantibodies to Lupus Nephritis.

Part II. Effector Mechanisms in Autoimmune Disease.

36. Dysregulation of the Vitamin D Nuclear Receptor MayContribute to the Higher Prevalence of Some Autoimmune Diseases inWomen.

37. Regulatory B Cells in Autoimmune Diseases : How Do TheyWork?

38. B-Lymphocyte Stimulator and a Proliferation-Inducing LigandSerum Levels in IgA-Deficient Patients With and Without CeliacDisease.

39. The IgM Response to Modified LDL in ExperimentalAtherosclerosis : Hy

Summary

This volume features key presentations from the 6th International Congress of Autoimmunity. The International Congress of Autoimmunity has become established as one of the major meetings in the field of immunology, with presentations covering every aspect of basic research in the hopes of clarifying pathogenesis of autoimmune disease as well as providing information on the latest innovations in biological and other modes of treatment. The goal of this volume is to present cutting edge research that focuses in particular on newer diagnostic tools and newer therapies for human autoimmune disease.

NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas.

ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Product details

• Authors: M. Eric Gershwin, Yehuda Shoenfeld, Yehuda (EDT)/ Gershwin Shoenfeld, Yehuda Gershwin Shoenfeld
• Assisted by: Eric Gershwin (Editor), M. E. Gershwin (Editor), M. Eric Gershwin (Editor), Yehud Shoenfeld (Editor), Yehuda Shoenfeld (Editor)
• Publisher: New york academy of sciences
• Languages: English
• Product format: Paperback / Softback
• Released: 30.10.2009
• EAN: 9781573317627
• ISBN: 978-1-57331-762-7
• No. of pages: 400
• Series: Annals of the New York Academy of Sciences; Annals of the New York Academy of Sciences
• Subjects: Natural sciences, medicine, IT, technology > Medicine; Medizin, Immunologie, Immunology, Autoimmunität, Medical Science