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This special volume of Progress in Molecular Biology and Translational Science focuses on oligomerization in health and disease.
List of contents
Section I. Structural, Physico-Chemical, and Evolutionary Aspects of Protein Oligomerization
- Evolutionary, Physico-Chemical and Functional Mechanisms of Protein Homooligomerization
- Structural, Evolutionary and Assembly Principles of Protein Oligomerization
- Physico-Chemical Principles of Protein Aggregation
- Structural Aspects of Amyloid Formation
Section II. Oligomerization in Seven-Transmembrane Receptors
- Quaternary Structure Predictions and Structural Communication Features of GPCR Dimers
- Challenges in the Development of Heteromer-GPCR-Based Drugs
- Oligomerization of GPCRs in Health and Disease on "Di/Oligomerisation of GPCRS; Mechanisms and Functional Significance"
- G Protein-Coupled Receptor Heterocomplexes in Neuropsychiatric Disorders
- Disease-Specific Heteromerization of G Protein-Coupled Receptors that Target Drugs of Abuse
Section III. Oligomerization in Ion Channels
- Social Networking among Voltage-Gated Potassium Channels
- Oligomerization of the Mitochondrial Protein VDAC1: From Structure to Function and Cancer Therapy
- Consequences of Dimerization of the Voltage Gated Proton Channel
- Receptor Heteromeric Assembly, How it Works and Why it Matters - The Case of Ionotropic Glutamate Receptors
Section IV. Oligomerization in Enzymes
- The Structural Basis for the Allosteric Regulation of Ribonucleotide Reductase
- Oligomerization of Dynamin Superfamily Proteins in Health and Disease
- Multimerization of the Dnmt3a DNA Methyltransferase and its Functional Implications
- Oligomerization in Endoplasmic Reticulum Stress Signaling
Section V. Oligomerization in Regulatory Proteins
- Toll-IL-1-Receptor-Containing Adaptor Molecule-1 (TICAM-1), a Signaling Adaptor Linking Innate Immunity to Adaptive Immunity
- Assembly of Gamma-Tubulin Ring Complexes: Implications for Cell Biology and Disease
- Chemokine Oligomerization in Cell Signaling and Migration
- Oligomerization of Rab/Effector Complexes in the Regulation of Vesicle Trafficking
Report
Praise for the series:
"Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal
