Inflammatory Bowel Disease and Familial Adenomatous Polyposis - Clinical Management and Patients' Quality of Life

Inflammatory bowel disease (IBD) and familial adenomatous polyposis (FAP) are complex diseases. Despite increased knowledge on the pathophysiological process, many aspects remain rather unclear, especially concerning IBD. This book gathers current methods of treatment of these diseases and also presents the management of their complications. The authors give a comprehensive overview of the newer therapies to bring readers up to date. Inflammatory bowel disease (IBD) and familial adenomatous polyposis (FAP) are complex diseases, which are subject to numerous medical researches. Despite increased knowledge on the pathophysiological process, many aspects remain rather unclear, especially concerning IBD. The genetic basis of FAP is well known, but there is still debate about IBD, which seems more likely to be a multifactorial disease, where the illness is due to interactions between environmental and genetic factors. In the near future, the aim will be to prevent these disorders and their sequelae through early detection and early intervention (for example genetic therapy). Unfortunately, we are still dealing with young patients with a lifelong disease course, leading to early morbidity (and in some cases mortality) and extended needs for medical treatment, with a consequent decrease in quality of life. IBD and FAP represent a challenge for a multidisciplinary medical approach where different personnel play major roles in different stages of the patient s treatment. It is in this light that basic scientists, geneticists, pathologists, radiologists, gastroenterologists, surgeons, psychologists and WOC/ET nurses have to work together in order to improve the outlook of these patients and their families.

Sommario

Section I GENERAL APPROACH.-Imaging in IBD and FAP.-Section II IBD.-IBD: epidemiology and risk factors.-IBD, the pathologist approach to the clinical problem.-Dsyplasia in IBD from genetics to treatment.-IBD: cancer risk and surveillance.-Colonic and anorectal motility in Inflammatory Bowel Disease.-Non invasive diagnostic tools in IBD.-Endoscopic evaluation in RCU.-Systemic complication of IBD.-Nutrition and malnutrition in IBD.-Probiotics and IBD.-Quality of life issues in IBD.-IBD and pregnancy.-Urinary and sexual complications in IBD.-Biological approach in the treatment of Chron's disease.-Medical management of fistulas in Crohn's disease.-Surgical options in small bowel Crohn's disease.-Crohn's disease of the colon.-Laparoscopic treatment of Crohn's disease.-Post operative prevention of relapse in Crohn s disease.-Surgical treatment of perineal Crohn s disease.-Medical management of ulcerative colitis.-Indications for surgical treatment of ulcerative colitis.-Surgical treatment of severe acute colitis.-Prophylatic surgery for longstanding ulcerative colitis: which options?.-Indications and technical details in stoma surgery for IBD.-Salvage surgery for pouch: possibilities and pitfalls.-Management of difficult ileal-pouch-anal anastomosis and stomas.-Open questions in restorative proctocolectomy.-Follow-up of restorative proctocolectomy: clinical experience of a specialized pouch clinic.-Management of pouchitis.-Bowel transplantation for inflammatory bowel disease.-Liver transplantation for primary sclerosing colangitis and inflammatory bowel disease.-Section III FAP.-Emergent issues and future trends in familial polyposis.-Genetic mutations in FAP and conventional or laparoscopic surgical approach.-Clinical significance of extra colonic manifestations in FAP patients .-Desmoid tumours in FAP.-The endoscopic procedures in familial adenomatous polyposis syndrome: a critical revue.-FAP's hystory throughout a patient s story.-Ileo-rectal anastosmosis versus ileo-anal pouch as the surgical treatment for familial adenomatous polyposis.-Surgery in FAP: follow-up of rectal stump.-Section IV SPECIAL TOPICS.-Psyche and colitis: what surgeons should know.-Interdisciplinary management of inflammatory bowel disease and familial adenomatous polyposis Ileoanal pouches and indeterminates colitis.-Quality of life in pouch patient.-The place of proctocolectomy with definitive ileostomy in the era of restorative proctocolectomy.-Surgical management of IBD emergencies: the approach in a peripheral hospital.-Management of the unhealed perineal wound.-Rehabilitation after surgery for IBD and FAP

Riassunto

Inflammatory bowel disease (IBD) and familial adenomatous polyposis (FAP) are complex diseases, which are subject to numerous medical researches. Despite increased knowledge on the pathophysiological process, many aspects remain rather unclear, especially concerning IBD. The aim of the researchers will be to prevent these disorders through early detection and intervention, thanks to genetic therapy. This book gathers current methods of treatment of these diseases and also presents the management of their complications. Authors finally intend to give a comprehensive overview of the newer therapies to bring the readers up to date.

Testo aggiuntivo

From the reviews:

"Inflammatory Bowel Disease and Familial Adenomatous Polyposis, deals with the two diseases in its title, and there is an emphasis on surgery throughout the book … . This book reflects the author’s diagnostic and therapeutic expertise. Discussions are up to date, and current topics are well referenced. … The strength of the book is surgical technique and outcome, and for this reason I recommend it for surgeons in training and in clinical practice … ." (G. N. J. Tytgat, The New England Journal of Medicine, Vol. 356 (18), 2007)

Relazione

From the reviews: "Inflammatory Bowel Disease and Familial Adenomatous Polyposis, deals with the two diseases in its title, and there is an emphasis on surgery throughout the book . This book reflects the author s diagnostic and therapeutic expertise. Discussions are up to date, and current topics are well referenced. The strength of the book is surgical technique and outcome, and for this reason I recommend it for surgeons in training and in clinical practice ." (G. N. J. Tytgat, The New England Journal of Medicine, Vol. 356 (18), 2007)

Dettagli sul prodotto

• Autori: S. M. Goldberg
• Con la collaborazione di: G. G. Delaini (Editore), Gian Gaetano Delaini (Editore), Gia Gaetano Delaini (Editore), Gian Gaetano Delaini (Editore), S.M. Goldberg (Prefazione)
• Editore: Springer, Berlin
• Lingue: Inglese
• Formato: Copertina rigida
• Pubblicazione: 01.01.2006
• EAN: 9788847004337
• ISBN: 978-88-470-0433-7
• Pagine: 482
• Peso: 1742 g
• Illustrazioni: Illustr.
• Categorie: Scienze naturali, medicina, informatica, tecnica > Medicina > Branche non cliniche; B, Medicine, Medical research, Surgery, Pathology, INTERNAL MEDICINE, Personal & public health, Gastroenterology, Public health & preventive medicine, colorectal surgery, Quality of Life Research, Rectum—Surgery