Next Generation Antibody Drug Conjugates (ADCs) and Immunotoxins

This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application. Lessons learned from the current state of the art are used to further improve our understanding of their mechanisms of action and off target activities.

The book introduces scientists to all of the prerequisites that must be properly addressed, including identification of the right target, specific traits of target binding antibodies, proper selection of the toxic payload, internalization induced by binding, and next generation conjugation and linker technologies. These knowledge-based, revolutionary new drug principles will form the cornerstone of the future standard of care and will lead to major advances in application, as well as improved quality of life and patient survival rates. This book will be of interest to biotech companies and researchers working in the fields of immunology, pharmacology, and oncology.

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• Con la collaborazione di: Ulf Grawunder (Editore), Stefan Barth (Editore), Ul Grawunder (Editore), Barth (Editore), Barth (Editore)
• Editore: Springer, Berlin
• Lingue: Inglese
• Contenuto: Libro
• Forma del prodotto: Tascabile
• Data pubblicazione: 01.01.2018
• Categoria: Scienze naturali, medicina, informatica, tecnica > Medicina > Farmacia
• EAN: 9783319836096
• ISBN: 978-3-31-983609-6
• Numero di pagine: 181
• Illustrazioni: XI, 181 p. 57 illus., 39 illus. in color.
• Dimensioni (della confezione): 15.5 x 1 x 23.5 cm
• Peso (della confezione): 308 g
• Serie: Milestones in Drug Therapy; Milestones in Drug Therapy
• Categorie: Onkologie, B, Krankheiten und Störungen, Immunology, INTERNAL MEDICINE, Oncology, Pharmacology, Health Sciences, Biomedical and Life Sciences, Cancer Research, Biomedical Research, pharmacotherapy, Pharmacology/Toxicology, Therapy and therapeutics, Diseases and disorders, Antibodies